응용화학생명공학과 교수 목록 - 응용화학생명공학과

교수진
교수

교수정보의 상세 화면
이름 김용성 학력 박사 전공 응용화학생명공학전공(과)
정보	연구실 : 팔달관 802호 연구실번호 : 2662 이메일 : kimys@ajou.ac.kr 연구관심분야 : 항체공학, 차세대 종양 치료용 항체 개발, 단백질 공학, 홈페이지1 : http://antibody.ajou.ac.kr
학력	졸업연도/학교/학위 2002.12 Univ Colorado Health Sci Center 박사 졸업연도/학교/학위 1998.02 한국과학기술원 석사 졸업연도/학교/학위 1996.02 서울대학교 학사
경력	2013.01 ~ 2013.12 : Consultant, CJ Pharmaceutics 2010.09 ~ 2011.08 : Visiting Scholar (Sabbatical) at Genentech Inc. (San Francisco, USA) 2004.03 ~ present : Assistant, Associate, and then full Professor at Dept. of Molecular Science and Technology, Ajou University 2002.11 ~ 2004.02 : Postdoctoral Associate at Division of Biological Engineering, Massachusetts Institute of Technology (MIT) 1998.02 ~ 1999.01 : Research Assistant, Korea Research Institute of Bioscience and Biotechnology. 1990.08 ~ 1992.02 : Military Service at Army in Republic of Korea.
연구분야	? Development of next generation antibody platform technology ? Therapeutic antibody and protein engineering ? Non-antibody alternative scaffold development based on Kringle domain ? Development of cell/tissue-specific cell-penetrating antibody as anti-cancer and anti-viral agents
논문 및 연구활동	연구활동(주요논문) [논문] 김용성, 정기준, 김애영, 김철호, 박경진, 이창한, Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.287 , No.5 , pp.3313 -3325 (Jan, 2012) [논문] 김용성, 박경진, 성은실, 권명희, 최지다, 김정선, 김수현, 이창한, 김애영, Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.107 , No.21 , pp.9567 -9571 (May, 2010) [논문] 김용성, 권명희, 김정선, 이우람, 장지영, Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies , NUCLEIC ACIDS RESEARCH , Vol.38 , No.5 , pp.1596 -1609 (Mar, 2010) [논문] 김용성, 광운재, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유희, A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes. Molecular Cancer Therapeutics. , MOLECULAR CANCER THERAPEUTICS , Vol.8 , No.8 , pp.2276 -2285 (Aug, 2009) [논문] 김용성, 김정선, 정종근, 장지영, 전혜령, 권명희, 이석찬, A nucleic acid-hydrolyzing antibody penetrates into cells via Caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity. , CELLULAR AND MOLECULAR LIFE SCIENCES , Vol.66 , No.1 , pp.1985 -1997 (Jun, 2009) 국제학술논문지 [논문] 김용성, 권혁상, 김보민, 홍다해, 신초롱, 양석우, 이성욱, 이영민, 고종희, 민기홍, Preclinical efficacy and safety of an anti-human VEGFA and anti-human NRP1 dual-targeting bispecific antibody , BIOMOLECULES , pp.1 -18 (Jun, 2020) [논문] 김용성, 신승민, 박성욱, 최동기, 권혜진, 이다근, 조용범, 김지선, 전세용, Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth , SCIENCE ADVANCES , pp.1 -18 (Jan, 2020) [논문] 김용성, 전세용, 김지선, Critical issues in the development of immunotoxins for anticancer therapy , JOURNAL OF PHARMACEUTICAL SCIENCES , pp.104 -115 (Jan, 2020) [논문] 김용성, 김정아, 김예진, 김철호, 함석진, 정근옥, 이현우, A neuropilin-1 antagonist exerts anti-tumor immunity by inhibiting the suppressive function of intratumoral regulatory T cells , CANCER IMMUNOLOGY RESEARCH , pp.46 -56 (Jan, 2020) [논문] 김용성, 백두산, 조병철, 박대찬, 강한나, 김예진, 이세영, Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFRtargeted antibody therapy in KRAS-mutant non-small cell lung cancer , CANCER LETTERS , pp.23 -34 (Dec, 2019) [논문] 김용성, 박해심, 김정아, 김승현, 김정은, 정근옥, Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity , SCIENTIFIC REPORTS , pp.1 -12 (May, 2019) [논문] 홍순선, 강여울, 우민규, 박정희, 전민지, 한보름, Zhenghuan Fang, Hong Hua Yan, 김수정, 손미권, 신승민, 이지은, 정경희, 김용성, 임주한, KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer , CANCER LETTERS , Vol.438 , pp.174 -186 (Dec, 2018) [논문] 김용성, 박재영, 최동기, 박성욱, 전세용, 홍진선, 김지선, 신승민, Engineering of a tumor cell-specific, cytosol-penetrating antibody with high endosomal escape efficacy , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.503 , No.4 , pp.2510 -2516 (Sep, 2018) [논문] 김욱, 정다은, 허성은, Eunbyul Ji, 노준기, Eun Kyung Lee, Sojin Ahn, 김예진, 김용성, Suk Woo Nam, Rohit N. Kulkarni, Kyoung Bun Lee, Chongtae Kim, Myeongwoo Jung, Reduced RNA-binding protein HuD in pancreatic neuroendocrine tumors lowers p27Kip1 levels linked to poor prognosis , JOURNAL OF PATHOLOGY , pp.1 -36 (Aug, 2018) [논문] 김철호, 이복순, 김연수, 김대호, 원호륜, 김용성, 김행준, HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cells , SCIENTIFIC REPORTS , Vol.8 , pp.1 -8 (Aug, 2018) [논문] 김용성, 하지희, 김철호, 김정아, 김예진, 정근옥, 김정은, Heterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8+ T cells. , ONCOIMMUNOLOGY , Vol.7 , No.7 (Mar, 2018) [논문] 김용성, 김정호, 김예진, 백두산, An Immunoglobulin Fc-fused Peptide without C-terminal Arg or Lys Residue Augments Neuropilin-1-dependent Tumor Vascular Permeability , MOLECULAR PHARMACEUTICS , pp.394 -402 (Feb, 2018) [논문] 김용성, 백두산, 김수정, 김성훈, 강수진, 양원숙, 송지애, 이무승, 김정호, 서우영, Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification , SCIENTIFIC REPORTS , Vol.7 , pp.1 -13 (Nov, 2017) [논문] 김용성, 신승민, 최동기, 배점일, 김지선, 박성욱, 송기훈, 정근옥, Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration , NATURE COMMUNICATIONS , pp.1 -14 (May, 2017) [논문] 김용성, 홍순선, 백두산, 정근옥, 김예진, Co-targeting of EGF receptor and neuropilin-1 overcomes cetuximab resistance in pancreatic ductal adenocarcinoma with integrin b1-derived Src-Akt bypass signaling , ONCOGENE , Vol.36 , No.18 , pp.2543 -2552 (May, 2017) [논문] 김용성, 김수현, 이시영, 곽아름, 김시내, Tam Thanh Nguyen, Gaae Gil, 김은혜, 유광하, 김인애, 이영민, 전현정, Edward D. Chan, Xiyuan Bai, 김현우, 최동기, IL-32-induced inflammatory cytokines are selectively suppressed by a1-antitrypsin in mouse bone marrow cells , IMMUNE NETWORK , Vol.17 , No.2 , pp.116 -120 (Apr, 2017) [논문] 김용성, 하지희, Guang Wu, 김동범, 박병권, 박상규, 이수인, Avishekh Gautam, 김정남, 박한범, 권형주, 이영희, 김태하, Anti-metastatic effect of the TM4SF5-specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model , ONCOTARGET , Vol.7 , No.48 , pp.79710 -79186 (Nov, 2016) [논문] 김용성, 김정은, 하지희, Immunoglobulin Fc heterodimer platform technology: From design to applications in therapeutic antibodies and proteins , FRONTIERS IN IMMUNOLOGY , pp.1 -16 (Oct, 2016) [논문] 유태현, 김용성, 박성욱, 김동명, 오찬희, 이경호, 양성윤, 박지호, 민승의, Cell-free production and streamlined assay of cytosol-penetrating antibodies , BIOTECHNOLOGY AND BIOENGINEERING , pp.2107 -2112 (Oct, 2016) [논문] 김용성, 김수현, 이시영, 김은솜, 정현정, 홍재우, 곽아름, 조승현, 배수영, 이종호, 김부산, 이정민, 윤설아, 김소미, 김미연, 김현우, 이영민, 최동기, Proinsulin Shares a Motif with Interleukin-1α (IL-1α) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1* , JOURNAL OF BIOLOGICAL CHEMISTRY , pp.14620 -14627 (Jul, 2016) [논문] 김용성, 김수현, 조승현, 김은솜, 곽아름, 이정민, 홍재우, 이종호, 윤설아, 배수영, 김부산, 류소윤, 강태봉, Erk Her, 이영민, 정현정, 최동기, Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Rα though a common chain IL-1R3 (IL-1RAcP) shared with IL-1 , CYTOKINE , pp.33 -40 (Jul, 2016) [논문] 김용성, 최동기, 조현수, 신승민, 박성욱, 김지선, 신주연, Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape , JOURNAL OF CONTROLLED RELEASE , pp.165 -175 (Jun, 2016) [논문] 김용성, 하지희, 권형주, 김동범, 이영희, Guang Wu, 박병권, 이근욱, 김태하, Extracellular Release of CD11b by TLR9 Stimulation in Macrophages , PLoS ONE , pp.1371 -1384 (Mar, 2016) [논문] 김철호, 이복순, 장재원, Hyung Kwon Byeon, 한재호, 김용성, 신유섭, 차현영, 박주경, Downregulation of Nrf2 by the combination of TRAIL and Valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of Bcl-xL , CANCER LETTERS , Vol.372 , No.1 , pp.65 -74 (Mar, 2016) [논문] 김용성, 김예진, 최동기, 최혜지, Engineering of immunoglobulin Fc heterodimers using yeast surface-displayed combinatorial Fc library screening , PLoS ONE , Vol.10 , No.12 , pp.1 -20 (Dec, 2015) [논문] 김용성, 최동기, 김동명, 신승민, 배점일, 유태현, 김지선, 박성욱, Quantitative assessment of cellular uptake and cytosolic access of antibody in living cells by an enhanced split GFP complementation assay , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.467 , No.4 , pp.771 -777 (Nov, 2015) [논문] 김용성, 배점일, 신태환, 박지호, 김석기, 정문경, 한윤호, 김예진, 강세훈, Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis , JOURNAL OF CONTROLLED RELEASE , Vol.216 , pp.56 -68 (Oct, 2015) [논문] 김용성, 김예진, 석승현, 서민덕, 최혜지, Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation , MOLECULAR IMMUNOLOGY , Vol.65 , No.2 , pp.377 -383 (Jun, 2015) [논문] 김용성, 백두산, Humanization of a phosphothreonine peptide-specific chicken antibody by combinatorial library optimization of the phosphoepitope-binding motif , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.463 , No.3 , pp.414 -420 (May, 2015) [논문] 김용성, 김성훈, 배점일, 신주연, 최동기, 신승민, A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells , MABS , Vol.6 , No.6 , pp.1402 -1414 (Nov, 2014) [논문] 김용성, Gu Min Jeong, Ki Jun Jeong, Sung Gap Im , Hyejeong Seong, Site-specific immobilization of proteins on non-conventional substrates via solvent-free initiated chemical vapour deposition(iCVD) process , POLYMER CHEMISTRY , No.15 , pp.4459 -4465 (Aug, 2014) [논문] 정기준, 이용재, 김용성, 정구민, High-level production of Fc-fused kringle domain in Pichia pastoris , JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY , Vol.41 , No.6 , pp.989 -996 (Jun, 2014) [논문] 김용성, Govindan Raghunathan, Ganapathiraman Munussami, Sun-Gu Lee, Hyun-jong Paik, Seong Soo A An, Sebyung Kang , Hyojin Moon, A variant of green fluorescent protein exclusively deposited to active intracellular inclusion bodies , MICROBIAL CELL FACTORIES , Vol.13 , pp.1 -11 (May, 2014) [논문] 정기준, 김용성, 정구민, A human kringle domain-based fluorescence-linked immunosorbent assay system , ANALYTICAL BIOCHEMISTRY , Vol.451C , pp.63 -68 (Apr, 2014) [논문] 김용성, 백두산, Construction of a large synthetic human Fab antibody library on yeast cell surface by optimized yeast mating , JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY , Vol.24 , No.3 , pp.408 -420 (Mar, 2014) [논문] 김용성, 성은실, 이영돈, 김기수, 김세호, 김석기, 신태환, 김예진, Enhancement of the tumor penetration of monoclonal antibody by fusion of a neuropilin-targeting peptide improves the antitumor efficacy , MOLECULAR CANCER THERAPEUTICS , Vol.13 , No.3 , pp.651 -661 (Mar, 2014) [논문] 김용성, 김예진, 이상호, 최혜지, A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent anti-tumor activity , MOLECULAR CANCER THERAPEUTICS , Vol.12 , No.12 , pp.2748 -2759 (Dec, 2013) [논문] 김철호, 차현영, 이복순, 강샘, 장재원, 성은실, 최재원, 김장희, 김용성, 신유섭, Valproic Acid Sensitizes TRAIL-Resistant Anaplastic Thyroid Carcinoma Cells to Apoptotic Cell Death , ANNALS OF SURGICAL ONCOLOGY , Vol.20 , No.3 (Dec, 2013) [논문] 이석찬, 이건섭, 심혜경, 권명희, 손수완, 박을용, 이택균, 이우람, 안중균, 김동균, 김용성, 김기윤, A nucleic acid hydrolyzing recombinant antibody confers resistance to curtovirus infection in tobacco , PLANT CELL TISSUE AND ORGAN CULTURE , Vol.115 , No.2 , pp.179 -187 (Nov, 2013) [논문] 이석찬, 심혜경, 권명희, 손수완, 김기윤, Yang Jin-Kwon, 이택균, 오중균, 김동균, 이건섭, 김용성, 박을용, RNA virus accumulation is inhibited by ribonuclease activity of 3D8 scFv in transgenic Nicotiana tabacum , PLANT CELL TISSUE AND ORGAN CULTURE , Vol.115 , No.2 , pp.189 -197 (Nov, 2013) [논문] 김철호, 이복순, 신유섭, 김용성, 차현영, AY4, an agonistic anti-death receptor 4 MAB, induces apoptotic cell death in anaplastic thyroid cancer cells via downregulation of Bcl-xL with reactive oxygen species generation , ENDOCRINE-RELATED CANCER , Vol.20 , No.3 , pp.283 -291 (May, 2013) [논문] 권명희, 우민영, 팜딘츄옹, 김용성, 박선, An Anti-Nucleic Acid Antibody Delivers Antigen to the Cross-Presentation Pathway in Dendritic Cells and Potentiates Therapeutic Antitumor Effects , JOURNAL OF IMMUNOLOGY , Vol.189 , No.12 , pp.5755 -5763 (Dec, 2012) [논문] 김용성, 신태환, 권명희, 팜딘츄옹, 최동기, 김애영, 신승민, Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide , PLoS ONE , Vol.7 , No.12 (Dec, 2012) [논문] 김철호, 이복순, 강성운, 성은실, 신유섭, 임영창, 김용성, 황혜숙, An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation , CANCER LETTERS , No.1 , pp.45 -57 (Sep, 2012) [논문] 김철호, 강성운, 신유섭, 김용성, 성은실, 이복순, 황혜숙, An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation , Cancer letters , pp.45 -57 (Sep, 2012) [논문] 김용성, 김철호, 최혜지, 성은실, 박경진, The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells , EXPERIMENTAL CELL RESEARCH , No.13 , pp.1564 -1576 (Aug, 2012) [논문] 김용성, 변승준, 권명희, 김애영, 이자영, Viral genome RNA degradation by sequence-selective, nucleic-acid hydrolyzing antibody inhibits the replication of influenza H9N2 virus without significant cytotoxicity to host cells. , ANTIVIRAL RESEARCH , pp.157 -167 (May, 2012) [논문] 김용성, 권명희, 성은실, 윤지선, 김애영, 최동기, Interfering transbody-mediated Her2 gene silencing induces apoptosis by G0/G1 cell cycle arrest in Her2-overexpressing SK-BR-3 breast cancer cells , BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , No.2 , pp.413 -419 (Apr, 2012) [논문] 김용성, 정기준, 김애영, 김철호, 박경진, 이창한, Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.287 , No.5 , pp.3313 -3325 (Jan, 2012) [논문] 박천석, 이길용, 정종현, Jantra Hansin, 하석진, 차재호, 김용성, 서동, Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB1 on Saccharomyces cerevisiae , BIORESOURCE TECHNOLOGY , No.19 , pp.9179 -9184 (Oct, 2011) [논문] 정기준, 이창한, 김용성, 장승훈, High level production of a kringle domain variant by high-cell-density cultivation of Escherichia coli , APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , No.2 , pp.327 -336 (Oct, 2011) [논문] 김용성, 박경진, 김애영, 권오석, 정기준, 이창한, 김상직, Generation of bivalent and bispecific Kringle single domains by loop grafting as potent agonists against death receptor 4 and 5 , JOURNAL OF MOLECULAR BIOLOGY , No.1 , pp.201 -219 (Aug, 2011) [논문] 권명희, 김동식, 김용성, 정종근, A Tat-grafted anti-nucleic acid antibody acquires nuclear-localization property and a preference for TAR RNA , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , No.3 , pp.403 -407 (Mar, 2011) [논문] 정준호, 심현보, 김용성, 윤수민, Current Perspectives on Therapeutic Antibodies , BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , Vol.15 , No.5 , pp.709 -715 (Oct, 2010) [논문] 김용성, 권명희, 박준성, 정준호, 성은실, 김애영, Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells , APOPTOSIS , Vol.15 , No.10 , pp.1256 -1269 (Oct, 2010) [논문] 김용성, 박경진, 성은실, 권명희, 최지다, 김정선, 김수현, 이창한, 김애영, Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.107 , No.21 , pp.9567 -9571 (May, 2010) [논문] 권명희, 전혜령, 추옹 팜 딘, 이석찬, 박선, 김용성, 임성인, An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus. , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.395 , No.4 , pp.484 -489 (May, 2010) [논문] 김용성, 송무영, 최혜지, 이창한, 최동기, Expression of soluble and functional human neonatal Fc receptor in Pichia pastoris. , PROTEIN EXPRESSION AND PURIFICATION , Vol.71 , No.1 , pp.42 -48 (Mar, 2010) [논문] 김용성, 권명희, 김정선, 이우람, 장지영, Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies , NUCLEIC ACIDS RESEARCH , Vol.38 , No.5 , pp.1596 -1609 (Mar, 2010) [논문] 김용성, 김진규, 성은실, 박혜란, 이승현, 박동운, Humanization of an agonistic anti-death receptor 4 single chain variable fragment antibody and avidity-mediated enhancement of its cell death-inducing activity , MOLECULAR IMMUNOLOGY , Vol.47 , No.4 , pp.816 -824 (Jan, 2010) [논문] 김용성, 김창구, 김세호, 장기환, 신용원, 류경환, 홍광원, 이승현, A novel anti-EGFR monoclonal antibody inhibiting tumor cell growth by recognizing different epitopes from cetuximab , JOURNAL OF BIOTECHNOLOGY , Vol.145 , pp.84 -91 (Jan, 2010) [논문] 김용성, 이석찬, 권석태, 김동균, 최정진, 양주성, 이용, 정균오, 정유철, 권명희, 심혜경, Production of recombinant single chain antibodies (scFv) in vegetatively reproductive Kalanchoe pinnata by in planta transformation , PLANT CELL REPORTS , Vol.28 , No.10 , pp.1593 -1602 (Oct, 2009) [논문] 김용성, 광운재, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유희, A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes. Molecular Cancer Therapeutics. , MOLECULAR CANCER THERAPEUTICS , Vol.8 , No.8 , pp.2276 -2285 (Aug, 2009) [논문] 김용성, 김정선, 정종근, 장지영, 전혜령, 권명희, 이석찬, A nucleic acid-hydrolyzing antibody penetrates into cells via Caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity. , CELLULAR AND MOLECULAR LIFE SCIENCES , Vol.66 , No.1 , pp.1985 -1997 (Jun, 2009) [논문] 김용성, 정준호, 이창한, 박경진, 이승현, 권명희, 장지영, Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.382 , No.4 , pp.726 -729 (May, 2009) [논문] 박기동, 김용성, 정윤기, 권명희, 손세진, 이우람, Optimized stability retention of a monoclonal antibody in the PLGA nanoparticles , INTERNATIONAL JOURNAL OF PHARMACEUTICS , Vol.368 , No.1-2 , pp.178 -185 (Feb, 2009) [논문] 김용성, 이승현, 이석찬, 김동식, 권명희, 김정선, Generation of humanized anti-DNA hydrolyzing catalytic antibodies by complementarity determining region grafting. , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.379 , No.2 , pp.314 -318 (Feb, 2009) [논문] 김인섭, 최용운, 성학모, 손기환, 김용성, 강용, Improvement of virus safety of an antihemophilic factor IX by virus filtration process , Journal of Microbiology and Biotechnology , Vol.18 , No.7 , pp.1317 -1325 (Jul, 2008) [논문] 김정선, 박석열, 이석찬, 이우람, 권명희, 김용성, Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals , Proteins:structure, function, and bioinformatics (Wiley-Liss Inc.) , Vol.71 , No.4 , pp.2091 -2096 (Jun, 2008) [논문] 김정선, 정치훈, 이지은, 박석열, 이상학, 김용성, 고소케 니시, High resolution structure of ybfF from Escherichia coli K12: a unique substrate-binding crevice generated by domain arrangement , Journal of Molecular Biology (Elsevier) , Vol.376 , No.5 , pp.1426 -1437 (Mar, 2008) [논문] 김정선, 최지우, 고소케 니시, 이지은, 김용성, 정치훈, Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and without FMN cofactor , Journal of Molecular Biology (Elsevier) , Vol.377 , No.1 , pp.258 -267 (Mar, 2008) [논문] 백광희, 곽원재, 김창석, 김민수, 봉기태, 송무영, 유태형, 이병규, 김용성, 박상구, Characterization of a novel anti-human TNF- murine monoclonal antibody with high binding affinity and neutralizing activity , Experimental and Molecular Medicine , Vol.40 , No.1 , pp.35 -42 (Feb, 2008) [논문] 김용성, 이승현, 이병규, 김민수, 송무영, 유태형, Comparative analyses of complex formation and binding sites between human tumor necrosis factor-alpha and its three antagonists elucidate their different neutralizing mechanisms , Journal of Molecular Biology , Vol.374 , No.5 , pp.1374 -1388 (Dec, 2007) [논문] 김용성, 김정선, 콘, 김태인, 이현욱, 권명희, 진문수, Inducing rigid local structure around the zinc-binding region by hydrophobic interactions enhances the homotrimerization and apoptotic activity of zinc-free TRAIL , Biochemical and Biophysical Research Communications , Vol.362 , No.3 , pp.766 -772 (Oct, 2007) [논문] 김용성, 최경숙, 장지원, 이해원, 김태인, 박경진, 이승현, 이창한, 권명희, 김은희, A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. , Cancer Research , Vol.67 , No.15 , pp.7327 -7334 (Aug, 2007) [논문] 장영주, 이현욱, 이유리, 김용성, 권용순, Effect of a novel fully human monovalent antigen-binding fragment on the survival of cancer cell lines , Oncology Reports , Vol.18 , No.2 , pp.513 -517 (Aug, 2007) [논문] 김용성, 김민수, 최혜영, 김진국, 최용수, Optimized Serological Isolation of Lung-Cancer-associated antigens from a Yeast Surface-expressed cDNA library. , Journal of Microbiology and Biotechnology , Vol.17 , No.6 , pp.993 -1001 (Jun, 2007) [논문] 유연우, 서진호, 강희윤, 김용성, Flocculation of an isolated flocculent yeast, Candida tropicalis HY200, and its application for efficient xylitol production using repeated-batch cultivation , Journal of Microbiology and Biotechnology , Vol.16 , No.12 , pp.1874 -1881 (Dec, 2006) [논문] John F. Carpenter, Theodore W. Randolph, Matthew B. Seefeldt, 김용성, High-pressure studies on protein aggregates and amyloid fibrils , Methods in Enzymology , Vol.413 , No.1 , pp.237 -253 (Oct, 2006) [논문] 김용성, 이해원, 박경진, 이승현, 권명희, 김정선, Construction and characterization of a pseudo-immune human antibody library using yeast surface display , Biochemical and Biophysical Research Communications , Vol.346 , No.3 , pp.896 -903 (Aug, 2006) [논문] 유연우, 윤기선, 강현우, 고권혜, 김용성, 서주원, Characterization of S-adenosylmethionine synthetase from Streptomyces avermitilis NRRL8165 and its effect on antibiotic production , Enzyme and Microbial Technology(ELSEVIER) , Vol.39 , No.3 , pp.466 -473 (Jul, 2006) [논문] 김용성, 김정선, 이석찬, 이우람, 김영림, 손종남, 이승현, 정유철, 권명희, 심혜경, Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. , The Journal of Biological Chemistry , Vol.281 , No.22 , pp.15287 -15295 (Jun, 2006) [논문] 권대혁, 서진호, 이종화, 신재윤, 이종복, 김용성, 신연균, Membrane Topology of Helix 0 of the Epsin N-terminal Homology Domain. , Molecules and Cells , Vol.21 , No.3 , pp.428 -435 (Jun, 2006) [논문] Springer, TA, Wittrup, KD, 진문수, Carman, CV, Gang Song, Shimaoka, M, 김용성, Astrof, NS, Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.103 , No.15 , pp.5758 -5763 (Apr, 2006) [논문] 김용성, Rashna Bhandari, K. Dane Wittrup, Jennifer R. Cochran, John Kurian, Directed Evolution of the epidermal growth factor receptor extracellular domain for expression in yeast , PROTEINS:Structure, Function,and Bioinformatics , Vol.62 , pp.1026 -1035 (Mar, 2006) [논문] Wittrup, KD, Rao, B, Lippow, SM, 김용성, Cochran JR, Improved Mutants from Directed Evolution are Biased to Orthologous Substitutions , Protein Engineering, Design and Selection , Vol.19 , No.6 , pp.245 -253 (Mar, 2006) [논문] 김용성, 이승현, Byeong S.Chang, John F. Carpenter, Theodore W. Randolph, Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure , Protein Science , Vol.15 , pp.304 -313 (Feb, 2006) [논문] 유연우, 최기섭, 김윤정, 윤기선, 김용성, 김승범, Screening and characterization of a novel esterase from a metagenomic library , Protein Expression and Purification(ELSEVIER) , Vol.45 , No.2 , pp.315 -323 (Feb, 2006) [논문] 유연우, 서진호, 최기섭, 김용성, Restricted electron flux increases coenzyme Q10 production in Agrobacterium tumefaciens ATCC4452 , Process Biochemistry(Elsevier) , Vol.40 , No.10 , pp.3225 -3229 (Oct, 2005) [논문] Theodore W. Randolph, Matthew B. Seefeldt, Jim Seely, Kevin P. Tolley, 김용성, John F. Carpenter, High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: Thermodynamics, kinetics, and application to accelerated formulation studies , Protein Science , Vol.14 , No.1 , pp.2258 -2266 (Sep, 2005) [논문] 김용성, 이현욱, 이승현, 이해원, 권명희, 유연우, Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors , Biochemical and Biophysical Research Communications , Vol.330 , pp.1205 -1212 (May, 2005) [논문] 유연우, 황병희, 박창열, 김진욱, 김용성, 박장서, High-level production of arachidonic acid by fed-batch culture of Mortierella alpina using NH4OH as a nitrogen source and pH control , Biotechnology Letters(Springer Science) , Vol.27 , No.10 , pp.731 -735 (May, 2005) [논문] 유연우, 강희윤, 김근중, 김용성, 서진호, Screening and Characterization of Flocculent Yeast, Candida sp. HY200, for the Production of Xylitol from D-Xylose , Journal of Microbiology and Biotechnology , Vol.15 , No.2 , pp.362 -367 (Apr, 2005) [논문] TG Johns, AM Scott, AW Burgess, KD wittrup, EC Nice, J Rothacker, JR Cochran, MJ Olsen, NE Hall, PA Hoyne, TE Adams, AA Jungbluth, CW Ward, F Walker, G Ritter, KD Wittrup, LJ Old, 김용성, Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor , The Journal of Biological Chemistry , Vol.279 , No.29 , pp.30375 -30384 (Jul, 2004) [논문] K. Dane Wittrup, Rashna Bhandari, Mark J. Olsen, 김용성, Jennifer R. CoChran, Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments , Journal of Immunological Methods , Vol.287 , No.1-2 , pp.147 -158 (Apr, 2004) 국제학술발표 [학술회의] 김용성, Direct targeting cytosolic proteins by IgG-format antibody , The essential protein engineering summit (Apr, 2019) [학술회의] 김용성, 정근옥, 김정은, Engineering of potent interleukin-4 receptor alpha antibodies , The essential prtoein engineering summit (Apr, 2019) [학술회의] 김용성, 김예진, 이세영, Dual-targeting EGF receptor and neuropilin-1 antibody can overcomes cetuximab resistance in pancreatic ductal adenocarcinoma , Antibody Engineering & Therapeutics Asia (Feb, 2019) [학술회의] 김용성, 김지선, Development of a tumor-specific cytosol penetrating antibody with enhanced endosomal escape efficiency , Antibody Engineering & Therapeutics Asia (Feb, 2019) [학술회의] 김용성, Direct targeting oncogenic Ras mutants by IgG-format cytosol-penetrating antibody , AACR Targeting RAS-Driven Cancers (Dec, 2018) [학술회의] 김용성, Targeting regulatory T cells for anti-cancer immunotherapy , International symposium on molecular imaging, nanomedicine, and biotherapeutics delivery (Nov, 2018) [학술회의] 김용성, 김지선, 김정아, Mechanism of CDR structural change mediate endosomal escape of cytosol-localizing antibody by acidic pH-sensing , Peptalk 2018 (Jan, 2018) [학술회의] 김용성, 신승민, 최동기, 전세용, Development of intracellular oncogenic KRas targeting antibody , Peptalk 2018 (Jan, 2018) [학술회의] 김용성, 백두산, 김예진, Dual-targeting of EGFR and Neuropilin-1 overcomes resistance to cetuximab in Pancreatic Ductal Adenocarcinoma , Peptalk 2018 (Jan, 2018) [학술회의] 김용성, 신승민, Generation of intact, human IgG format antibodies that penetrate into the cytosol of living cells , The 13th asian congress on biotechnology (Jul, 2017) [학술회의] 김용성, 김지선, 박재영, Elucidation of local structural change mediated endosome escape of cytosolic penetrating antibody in a pH-dependent manner , 2017 PEGS boston (May, 2017) [학술회의] 김용성, 최동기, 신승민, A novel strategy for generating intact, human IgG format antibodies that penetrate into the cytosol of living cells , 2017 PEGS boston (May, 2017) [학술회의] 김용성, 백두산, 최혜지, 김정은, Generation of heterodimeric Fc through directed evolution combined with yeast surface display , IBC's 26th Annual Antibody Engineering & Therapeutics (Dec, 2016) [학술회의] 김용성, 송기훈, 김지선, Mechanism of a cytosol-localizing antibody mediate endosomal escape by acidic pH-induced conformational changes in early endosome , IBC's 26th Annual Antibody Engineering & Therapeutics (Dec, 2016) [학술회의] 김용성, 박재영, 김지선, pH-dependent conformational change of CDR of cytosol-penetrating antibody mediate the endosomal escape , 2nd Annual PEGS Korea-The Essential Protein Engineering Summit 2016 (Sep, 2016) [학술회의] 김용성, 백두산, 김예진, Dual targeting of NRP1 and EGFR Overcomes Resistance to Cetuximab in Pancreatic Ductal Adenocarcinoma with Integrin beta1-driven Src-Akt Bypass Signaling , 2nd Annual PEGS Korea-The Essential Protein Engineering Summit 2016 (Sep, 2016) [학술회의] 김용성, 김정아, 김정은, 최혜지, Generation of immunoglobulin Fc heterodimers through yeast surface-displayed combinatorial Fc library screening , 2nd Annual PEGS Korea-The Essential Protein Engineering Summit 2016 (Sep, 2016) [학술회의] 김용성, 김정아, 최혜지, 김정은, Engineering Antibody Fc Heterodimers Through Directed Evolution Combined with Yeast Surface Display , 26th tRNA conference (Sep, 2016) [학술회의] 김용성, 전세용, 최동기, 신승민, A novel platform for generating intact, full-length human IgG antibodies that penetrate into the cytosol of living cells , 26th tRNA conference (Sep, 2016) [학술회의] 김용성, 백두산, 김정호, Humanizing chicken antibody that specifically binds to a phosphothreonine peptide through optimizaing the phosphoepitope-binding motif , 12th Annual PEGS Boston-The Essential Protein Engineering Summit 2016 (Apr, 2016) [학술회의] 김용성, 김예진, 정근옥, Immunoglobulin Fc-fused, neuropilin-1-specific peptide promotes tumor tissue penetration and shows anti-tumor efficacy via anti-angiogenesis activity , 12th Annual PEGS Boston-The Essential Protein Engineering Summit 2016 (Apr, 2016) [학술회의] 김용성, 박성욱, Quantification of cellular internalization and endosomal release of antibody in living cells by an enhanced split GFP complementaion assay , 12th Annual PEGS Boston-The Essential Protein Engineering Summit 2016 (Apr, 2016) [학술회의] 김용성, Antibody Engineering : Challenges & Opportunities , 제1회 하이원 신약개발 심포지아 (Jan, 2016) [학술회의] 김용성, 박성욱, 김지선, 신승민, 최동기, A Novel Platform of Full-length IgG Antibodies that Penetrate into the Cytosol of Living Cells , PEGS Korea, the essential protein engineering summit (Sep, 2015) [학술회의] 김용성, 백두산, 김정호, 김예진, Immunoglobulin Fc-fused, neuropilin-1-specific peptide enhances tumor tissue penetration and suppresses tumor growth via anti-angiogenesis , PEGS Korea, the essential protein engineering summit (Sep, 2015) [학술회의] 김용성, 김정은, 최혜지, 하지희, Understanding of preferred heterodimer Fc formation through crystal structure , PEGS Korea, the essential protein engineering summit (Sep, 2015) [학술회의] 김용성, Cytosol-Penetrating IgG Antibody and Its Application for Targeting Cytosolic Proteins , PEGS Korea, the essential protein engineering summit (Sep, 2015) [학술회의] 김용성, Cell-penetrating IgG Antibody and its application for anti-cancer therapeutics , IBC's 25th Annual Antibody Engineering & Therapeutics China (Aug, 2015) [학술회의] 김용성, 신주연, 배점일, 최동기, 신승민, General Approach of Generating Full-length IgG Antibodies that Penetrate into the Cytosol of Living Cells , IBC's 25th Annual Antibody Engineering & Therapeutics China (Aug, 2015) [학술회의] 김용성, 최혜지, 하지희, Crystallization of heterodimer Fc to understand favorable heterodimer formation , IBC's 25th Annual Antibody Engineering & Therapeutics China (Aug, 2015) [학술회의] 김용성, 김지선, 백두산, Humanization of a chicken antibody that specifically recognize the phosphothreonine peptide by optimzation of the phosphoepitope-binding motif , IBC's 25th Annual Antibody Engineering & Therapeutics China (Aug, 2015) [학술회의] 김용성, 김예진, 최혜지, Crystal structures of heterodimeric Fc reveal the molecular basis for favoring the heterodimer formation , Nano Korea 2015 (Jul, 2015) [학술회의] 김용성, 배점일, 신주연, 최동기, 신승민, A strategy for generating intact, full-legth IgG antibodies that internalize into the cytosol of living cells , Nano Korea 2015 (Jul, 2015) [학술회의] 김용성, 신승민, 배점일, 최동기, General approach of developing full-length IgG antibodies that penetrate into the cytosol of living cells , KMB 2015 42nd Annual meeting & International symposium (Jun, 2015) [학술회의] 김용성, 김예진, 배점일, 신태환, Neuropilin-1-Specific Fc-Fused Peptide Inhibits Tumor Growth by Suppressing Angiogenesis and Metastasis , PEGS Europe Protein & Antibody Engineering Summit (Nov, 2014) [학술회의] 김용성, 최혜지, 김예진, A Bispecific Antibody Based on Heterodimeric Fc Demonstrates Potent Anti-Tumor Efficacy by Targeting Met and VEGFR-2 Simultaneously , PEGS Europe Protein & Antibody Engineering Summit (Nov, 2014) [학술회의] 김용성, Antibody engineering for potent anti-cancer therapeutics , 2014 제 66회 일본생물공학회대회 (Sep, 2014) [학술회의] 김용성, Antibody Platform of Biocon : Antibody Engineering for Potent anti-Cancer Therapeutics , Korea-Sweden Collaboration Symposium (Apr, 2014) [학술회의] 김용성, 신태환, 김예진, 백두산, Improvement of the anti-tumor efficacy via enhanced the tumor penetrating monoclonal antibody by fusion of neuropilin-targeting peptide , IBC's 24th Annual Antibody Engineering & Therapeutics (Dec, 2013) [학술회의] 김용성, 최혜지, 신승민, 최동기, Newly Designed Heterodimeric Fc-Based Bispecific Antibody Simultaneously Targeting VEGFR-2 and Met for Enhanced Anti-Tumor Activity , IBC's 24th Annual Antibody Engineering & Therapeutics (Dec, 2013) [학술회의] 김용성, Development of platform technology for next generation antibody therapeutics , 대한화학회 제111회 총회,학술발표회 (Apr, 2013) [학술회의] 김용성, 성은실, MG132, the Proteasome Inhibitor, Potentiates Death Receptor Agonist-Induced Apoptotic Cell Death by Stabilization of tBid and Bik in Human Head and Neck Squamous Cell Carcinoma Cells , Fourth Annual PEGS Europe (Nov, 2012) [학술회의] 김용성, 최동기, 신승민, 최혜지, 신태환, Cellular Internalization Mechanism and Intracellular Trafficking of Filamentous M13 Phages Displaying a Cell-Penetrating Transbody and TAT Peptide , Fourth Annual PEGS Europe (Nov, 2012) [학술회의] 이창한, 김용성, Development of Non-Antibody Protein Scaffold Based on Kringle Domain , 2012 International Symposium & Annual Meeting of KSMB (Jun, 2012) [학술회의] 김용성, 성은실, 최동기, 신태환, 김애영, Cell penetrating 4MH2 antibody with Her2-gene selective hydrolyzing activity induces apoptosis by G0/G1 cell cycle arrest in Her2-overexpressing SK-BR-3 breast cancer , Antibodies Asia (Feb, 2012) [학술회의] 김용성, 박경진, 김철호, 성은실, The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells , Antibodies Asia (Feb, 2012) [학술회의] 김용성, Interfering Transbody: The new platform technology for cancer and viral therapy , Antibodies Asia (Feb, 2012) [학술회의] 김용성, 변승준, 권명희, 김애영, 이자영, Viral genome RNA degradation by sequence-selective, nucleic-acid hydrolyzing antibody inhibits the replication of influenza H9N2 virus without significant cytotoxicity to host cells , Antibodies Asia (Feb, 2012) [학술회의] 김용성, 김애영, 성은실, 이창한, 박경진, BiKD: bivalent and/or bispecific kringle domain variants , Antibodies Asia (Feb, 2012) [학술회의] 김용성, Kringle Domain As a Novel Protein Scaffold , Next Generation Protein Therapeutics Summit (Jun, 2011) [학술회의] 김용성, Interfering Transbody: A New Gene-Silencing Technology Mediated by Antibody” , IBC’s 21st Annual International Conference Antibody Engineering (Dec, 2010) [학술회의] 김용성, 권명희, 박준성, 정준호, 김애영, 성은실, Histone deacetylase inhibitors have synergistic effect on death receptor 4-mediated apoptotic cell death in human T-cell acute lymphoblastic leukemia cells , IBCs 21th Annual International Conference Antibody Engineering (Dec, 2010) [학술회의] 김용성, 김애영, 성은실, 이창한, 박경진, Bivalency and bispecificity on a single domain : Kringle domain scaffold , IBCs 21th Annual International Conference Antibody Engineering (Dec, 2010) [학술회의] 김용성, 권명희, 성은실, 박보영, 최동기, 김애영, Interfering transbody-mediated Her2 silencing induces apoptosis by G0/G1 cell cycle arrest in Her2-overexpressing breast cancer cells , IBCs 21th Annual International Conference Antibody Engineering (Dec, 2010) [학술회의] 김용성, 박경진, 최혜지, Affinity and stability improvement of an agonistic human antibody against TRAIL receptor 2 enhanced cell death inducing activity for ? various cancer cells , IBCs 21th Annual International Conference Antibody Engineering (Dec, 2010) [학술회의] 김용성, 권명희, 성은실, 박경진, 이창한, A novel agonistic Kringle domain against DR4/5, KD548-Fc, induced caspase independent apoptotic cell death by forming distinct DISC from that of TRAIL , 2010 KSABC International symposium , pp.321 -321 (Aug, 2010) [학술회의] 김용성, 권명희, 김정선, 이자영, 이우람, Engineering of an anti-DNA antibody light chain variable single domains for sequence specific binding to avian influenza virus mRNAs targeting , 2010 KSABC International symposium , pp.361 -361 (Aug, 2010) [학술회의] 김용성, 권명희, 박준성, 정준호, 성은실, 김애영, Histone deacetylase inhibitors enhance death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells , 2010 KSABC International symposium , pp.321 -321 (Aug, 2010) [학술회의] 김용성, 이창한, Development of protein scaffold based Plasminogen Kringle domain , 2010 KSABC International symposium , pp.354 -354 (Aug, 2010) [학술회의] 김용성, 이창한, 성은실, 박경진, TRAIL receptor 1 and 2 recruit riboflavin kinase to exert reactive oxygen species-mediated, caspase-independent apoptotic cell death , 2010 KSBMB Annual Meeting , pp.288 -288 (May, 2010) [학술회의] 김용성, 장지영, 권명희, 이우람, 김애영, Degradation of particular mRNA by cell-penetrating, target sequence-specific hydrolyzing antibodies , 2010 KSBMB Annual Meeting , pp.258 -258 (May, 2010) [학술회의] 김용성, 박경진, 이승현, 권명희, 박상구, 박유회, 곽원재, 성은실, 장윤선, AY4, a human TRAIL-receptor 1 agonistic antibody, induces cell death in various tumor cells , 2010 KSBMB Annual Meeting , pp.282 -282 (May, 2010) [학술회의] 김용성, 박혜란, 이승현, 박동운, 김진규, 성은실, Humanization of an Agonistic Anti-Death Receptor 4 Single Chain Variable Fragment Antibody and Avidity-Mediated Enhancement of the Cell Death-Inducing Activity. , IBC’s 20th Annual International Conference Antibody Engineering , Vol.1 , No.1 , pp.1 -1 (Dec, 2009) [학술회의] 김용성, 이창한, 성은실, 권명희, 박경진, A novel Anti-human DR4/5 Kringle domain, KD548-Fc, with tumoricidal activity induces caspase-independent cells death , IBC’s 20th Annual International Conference Antibody Engineering , Vol.1 , No.1 , pp.1 -1 (Dec, 2009) [학술회의] 김용성, 장지영, 이우람, 권명희, 김애영, Degradation of target mRNA by cell-penetrating, sequence-selective, nucleic-acid hydrolyzing , Antibody Engineering & Antibody Therapeutics , Vol.1 , No.1 , pp.1 -1 (Dec, 2009) [학술회의] 박기동, 김용성, 장지영, 권명희, 정윤기, 최종훈, Multi-drug releasing heparin nanoparticles efficient in the intracellular delivery , Society For Biomaterials; 2009 Annual Meeting and Exposition (Apr, 2009) [학술회의] 권명희, 김용성, 정의정, 전혜령, 추옹 팜 딘, 장지영, A catalytic antibody with nuclease activity, 3D8 single chain variable fragment, suppresses viral multiplication , Antibody Engineering , Vol.1 , No.1 (Dec, 2008) [학술회의] 권명희, 김용성, 장지영, 정종근, Cytoplasmic targeting endocytosis of a nucleic acid-hydrolyzing anti-DNA single chain variable fragment leads to cell death , Antibody Engineering , Vol.1 , No.1 (Dec, 2008) [학술회의] 김용성, 성은실, 이창한, 권명희, Development of a novel protein scaffold based on kringle domain fold , Antibody Engineering , Vol.1 , No.1 (Dec, 2008) [학술회의] 김용성, 곽원재, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유회, A novel monoclonal antibody against death receptor 4 induces apoptotic cell death in a variety of cancer cells , Antibody Engineering , Vol.1 , No.1 (Dec, 2008) [학술회의] 김용성, 김동식, 전혜령, 권명희, Humanization of a nucleic acid-hydrolyzing catalytic antibody by loop grafting to a stable framework , Antibody Engineering , Vol.1 , No.1 (Dec, 2008) [학술회의] 박기동, 정의정, 정윤기, 손세진, 권명희, 김용성, Cytoplasmic delivery of a monoclonal antibody with antiviral activity using PLGA nanoparticle , 8th World Biomaterials Congress 2008 , pp.942 -942 (May, 2008) [학술회의] 김용성, A novel human antibody inducing autophagic cell death in a variety of cancer cells , Theme: From concept to market , Vol.1 , No.1 , pp.181 -181 (Apr, 2008) [학술회의] 박기동, 정의정, 정윤기, S.Son, 권명희, 김용성, Monoclonal antibody (3D8 scFv) loaded PLGA nanoparticles: Evaluations of stability and intracellular uptake , 1st Asian Biomaterials Congress (Dec, 2007) [학술회의] 김용성, 이창한, 이승현, 권명희, 박경진, Synergistic effect of Anti-TRAIL receptor 2 scFv and Akt Inhibitor on TR2-mediated Autophagic Cell Death , Antibody Engineering , Vol.1 , No.1 , pp.1 -1 (Dec, 2007) [학술회의] 김정선, 김용성, 박석열, 이우람, 정의정, 권명희, 이석찬, High resolution structures of an anti-DNA catalytic antibody, 3D8 scFv, VH and VL domain and VL-small molecule complex , International Congress of Young Chemists “YoungChem2007) , Vol.1 , No.1 (Oct, 2007) [학술회의] 김용성, 이창한, 이승현, 권명희, 박경진, Development of an anti-cancer human antibody which specifically binds to death receptor 5 and induces nonapoptotic cell death in a variety of cancer cells without cytotoxicity on normal cells , Symbiosis (Journal of Biotechnology) , Vol.131 , No.2S (Sep, 2007) [학술회의] 김용성, 이병규, 김민수, 송무영, Binding site analysis of human tumor necrosis factor-alpha antagonists elucidate their neutralizing mechanisms , Symbiosis (Journal of Biotechnology) , Vol.131 (Sep, 2007) [학술회의] 김용성, 이창한, 이승현, 권명희, 박경진, Development of anti-cancer human antibody killing a broad spectrum of cancer cells by specifically binding to TRAIL receptor 2 , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.441 -441 (Jun, 2007) [학술회의] 김용성, Anti-Cancer Therapeutic Antibody Development Targeting an antigen with multiple signaling pathways , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.245 -246 (Jun, 2007) [학술회의] 김용성, 진문수, 이현욱, 콘, 권명희, 김태인, Engineering of Zn-depleted TRAIL for Maintaining Trimerization Ability and Biological Activity , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.440 -440 (Jun, 2007) [학술회의] 김용성, 송무영, 김민수, 이병규, Binding site analyses of Human Tumor Necrosis Factor-alpha antagonists elucidate their neutralizing mechanisms , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.263 -263 (Jun, 2007) [학술회의] 김용성, 이우람, 강유정, 권명희, Concatenated Single Domain Antibody Exhibits Cooperative Effects on the Affinity and Activity , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.442 -442 (Jun, 2007) [학술회의] 김용성, 조미영, 이창한, 권명희, 이승현, Antibody Affinity Maturation by Designing Mutation Frequency on the Complementarity Determining Regions , 2007 International Symposium & Annual Meeting of KMB , Vol.1 , No.1 , pp.438 -438 (Jun, 2007) [학술회의] 권명희, 이승현, 정의정, 김용성, Development of agonistic human scFv antibodies against human TRAIL receptor 1 , Antibody Engineering and immunotherapeutics for the 21st Century , Vol.1 , No.1 , pp.1 -1 (Dec, 2006) [학술회의] 김용성, 최경숙, 김은희, 이창한, 박경진, 이승현, 이해원, 권명희, 김태인, A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and -resistant cancer cells , Antibody Engineering and Immunotherapeutics for the 21st century , Vol.1 , No.1 , pp.1 -1 (Dec, 2006) [학술회의] 김용성, 이우람, 김민수, 김진국, 최혜영, Discovery of lung cancer specific biomarker using SEREX and Yeast surface display , Antibody Engineering and Immunotherapeutics for the 21st century , Vol.1 , No.1 , pp.1 -1 (Dec, 2006) [학술회의] 김용성, 이현욱, 이우람, 권명희, TRAIL engineering for the development of cancer-cell selective proapoptotic inducer , Antibody Engineering , Vol.1 , pp.1 -1 (Dec, 2005) [학술회의] 김용성, 김정선, 이우람, 김영림, 손종남, 이승현, 권명희, 이석찬, Characterization and biological application of DNA hydrolyzing catalytic antibody, 3D8 , Antibody engineering , Vol.1 , pp.1 -2 (Dec, 2005) [학술회의] 김용성, 이해원, 이승현, 권명희, 장영주, Development of proapoptotic human scFv antibodies against human death receptor 5 and death decoy receptor 1 from a pseudo-immune library , Antibody Engineering , Vol.1 , pp.1 -1 (Dec, 2005) [학술회의] 유연우, 윤기선, 고권혜, 김용성, 강현우, Overexpression effects of S-adenosylmethionine synthetase gene in Streptomyces avermitilis NRRL8165 and Streptomyces peucetius KCTC9039 , 18th FAOBMB Symposium , Vol.18 , No.1 , pp.126 -126 (Nov, 2005) [학술회의] 김용성, Characterization and application of DNA hydrolyzing Catalytic Antibody 3D8 , 2005 Annual International Conference , Vol.1 , pp.48 -48 (Oct, 2005) [학술회의] 유연우, 서진호, 최기섭, 김용성, Enhanced coenzyme Q10 contents by DO control and restricted respiration in Agrobacterium tumefaciens , 12th European Congress on Biotechnology(Journal of Biotechnology, Bringing Genomes to Life) , Vol.118 (Aug, 2005) [학술회의] 김용성, 이승현, Byeong S. Chang, John F. Carpenter, Hydrostatic High-pressure-Mediated protein refolding from inclusion body , 2005 Colorado Protein Stability Conference , Vol.1 , No.1 , pp.14 -14 (Jul, 2005) [학술회의] 김용성, 이승현, 이현욱, 권명희, Quantitative analysis of receptor-receptor interactions among death receptors and death decoy receptors and TRAIL engineering to develop a cancer-selective apoptotic inducer , 2005 Colorado Protein Stability Conference , Vol.1 , No.1 , pp.58 -58 (Jul, 2005) [학술회의] Randolph TW, Carpenter JF, Tolley, KP, Kendrick B., M.B. Seefeldt, Seely J., 김용성, Crouch C., High pressure studies of human interleukin-1 receptor antagonist: application to industrial aggregate refolding and accelerated formulation studies , 2005 Colorado Protein Stability Conference , Vol.1 , No.1 , pp.13 -13 (Jul, 2005) [학술회의] 김용성, 유연우, 이해원, 권명희, Development of human Fab antibodies against human death receptors and death decoy receptors from a phage display library , Biochemical engineering from genomics to human well-being , Vol.1 , No.1 , pp.147 -147 (May, 2005) [학술회의] 유연우, 신상흠, 김용성, Optimization of medium composition for avermectin production by Streptomyces avermitilis NRRL8165 , APBioChEC'05, Biochemical Engineering from Genomics to Human Well-Being , Vol.1 , No.1 , pp.214 -214 (May, 2005) [학술회의] 유연우, 최기섭, 안미선, 김용성, 서진호, Improved coenzyme Q10 content by dissolved oxygen control and respiration inhibitors in Agrobacterium tumefaciens ATCC4452 , APBioChEC'05, Biochemical Engineering from Genomics to Human Well-Being , Vol.1 , No.1 , pp.197 -197 (May, 2005) [학술회의] 유연우, 최기섭, 김윤정, 김용성, 김승범, Directed evolution of thermostable esterases for the enantioselectivity to (S)-ketoprofen ethylester , APBioChEC'05, Biochemical Engineering from Genomics to Human Well-Being , Vol.1 , No.1 , pp.163 -163 (May, 2005) [학술회의] 김용성, 장윤선, 이승현, High pressure mediated protein refolding from inclusion body , Biochemical engineering from genomics to human well-being , Vol.1 , No.1 , pp.163 -163 (May, 2005) [학술회의] 유연우, 윤상영, 김윤정, 김용성, 김승범, Cloning and characterization of thermostable esterase from Achaeoglobus fulgidus DSM4304 , 27th Symposium on Biotechnology for Fuels and Chemicals , Vol.27 , No.1 , pp.71 -71 (May, 2005) [학술회의] 유연우, 신상흠, 안미선, 김용성, Avermectin production by optimization of medium composition from Streptomyces avermitilis NRRL815 , 27th Symposium on Biotechnology for Fuels and Chemicals , Vol.27 , No.1 , pp.164 -164 (May, 2005) [학술회의] 유연우, 윤기선, 강현우, 고권혜, 김용성, 서주원, Cloning and characterization of S-adenosylmethionine synthetase gene from Sacchaopolyspora erythraea ATCC11635 and Streptomyces avermitilis NRRL8165 , 27th Symposium on Biotechnology for Fuels and Chemicals , Vol.27 , No.1 , pp.164 -164 (May, 2005) [학술회의] 유연우, 최형훈, 최기섭, 김용성, 서진호, Respiration-restrictive Agrobacterium tumefaciens ATCC4452 has improved coenzyme Q10 contents , 27th Symposium on Biotechnology for Fuels and Chemicals , Vol.27 , No.1 , pp.163 -163 (May, 2005) [학술회의] 김용성, 이해원, 안미선, 권명희, 유연우, Development of human scFv antibodies against human death receptor 5 from a huge phage displayed library , Forging a vision of the future in antibody engineering and therapeutics (Nov, 2004) [학술회의] 김용성, High pressure mediated high throughput protein refolding from inclusion body , Regular Fall International meeting , pp.131 -131 (Oct, 2004) [학술회의] 김용성, 이해원, 안미선, Efficient construction of a large human single chain antibody library using a novel phage display system , Regular international fall meeting , pp.755 -755 (Oct, 2004) [학술회의] 김용성, 장윤선, 이승현, High pressure mediated protein refolding from inclusion body , Regular Fall International meeting , pp.797 -797 (Oct, 2004) 국내학술발표 [학술회의] 김용성, Direct targeting oncogenic Ras mutants by IgG-format cytosol-penetrating , Korea Digestive Disease Week 2019 (Nov, 2019) [학술회의] 김용성, Cellular cytosol-penetrating antibody technology for targeting cytosolic proteins including KRAS mutant , NOV-FEBPS anti-cancer symposium (Nov, 2019) [학술회의] 김용성, Therapeutic antibody platform technology & cancer immunotherapy , 46th ANNUAL MEETING & INTERNATIONAL SYMPOSIUM (Jun, 2019) [학술회의] 김용성, Cellular cytosol-penetrating antibody technology and its applications , 대한화학회 (Apr, 2019) [학술회의] 김용성, Targeting regulatory T cells for anti-cancer immunotherapy , 2019 Biokorea (Apr, 2019) [학술회의] 김용성, 김지선, Generation of tumor-specific, cytosol-penetrating antibody with enhanced endosomal escape efficiency , 2019 ASK winter training workshop (Feb, 2019) [학술회의] 김용성, Therapeutic antibody platform technology & cancer immunotherapy , 글로벌신약연구소 심포지엄 (Nov, 2018) [학술회의] 김용성, 차세대 치료용 항체 기술 및 실용화 전략 , 국립암센터 의생명과학포럼 (Oct, 2018) [학술회의] 김용성, 김예진, 이세영, Cetuximab resistance in pancreatic ductal adenocarcinoma with integrin b1-driven bypass signaling can overcomes by dual-targeting EGF receptor and Neuropilin-1 , KMB 2018 (Jun, 2018) [학술회의] 김용성, 신승민, 최동기, 민경서, Intracellular oncogenic Ras mutants target antibody exhibit anti-tumor effects follwing systemic administration , KMB 2018 (Jun, 2018) [학술회의] 김용성, Beyond the limits of current immunocytokines; heterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8+ T cells , SNU CRI Symposium (Apr, 2018) [학술회의] 김용성, Inhibition of regulatory T cells by Fc-fused peptide induces anti-tumor immunity in immunocompetent mouse models , 한국실험동물학회동계심포지엄 (Jan, 2018) [학술회의] 김용성, 신승민, Development of antibody targeting intracellular activated ras proteins to block the interaction with effectors , 2017 ASK summer Workshop (Jun, 2017) [학술회의] 김용성, Antibody engineering for targeting intracellular oncogenic KRas mutants , 2017 한국생물공학회 춘계학술발표대회 및 국제심포지엄 (Apr, 2017) [학술회의] 김용성, Current status and prospect of cytoosl protein targeting biologics develeopment , 제 2회 하이원 신약개발 심포지아 (Jan, 2017) [학술회의] 김용성, 백두산, 김정호, Development of Sandwich ELISA-kit for Human PICP Quantification , KMB 2016 43rd annual meeting & international symposium (Jun, 2016) [학술회의] 김용성, 김예진, 최혜지, A heterodimeric fc-based bispecific antibody simultaneously targeting vegfr-2 and met exhibits potent anti-tumor activity , 2015 Research community for cellular fermentative metabolism (Feb, 2015) [학술회의] 김용성, 배점일, 오진영, 신태환, 김예진, Enhancement of tumor accumulation and penetration of monoclonal antibodies by fusion of a Sema3A-mimic peptide improves the anti-tumor efficacy in solid tumors , 2014 한국생물공학회 추계학술발표대회 및 국제심포지엄 (Oct, 2014) [학술회의] 김용성, 김지선, 백두산, Design and Generation of Fully Synthetic Human Fab Antibody Libraries with Large Diversity by Optimized Yeast Mating , 2014 한국생물공학회 추계학술발표대회 및 국제심포지엄 (Oct, 2014) [학술회의] 김용성, 최혜지, 하지희, 신승민, A Novel Heterodimeric Fc-based Bispecific Antibody Simultaneously Targeting Met and VEGFR-2 Demonstrate Potent Anti-Tumor Effect , 2014 한국생물공학회 추계학술발표대회 및 국제심포지엄 (Oct, 2014) [학술회의] 김용성, A General Strategy for Generating Intact, Full-length IgG Antibodies That Penetrate into The Cytosol of Living Cells , 2014 한국생물공학회 추계학술발표대회 및 국제심포지엄 (Oct, 2014) [학술회의] 김용성, 김예진, 최혜지, A heterodimeric fc-based bispecific antibody simultaneously targeting vegfr-2 and met show potent anti-tumor activity , 2014 KSBMB Annual Meeting (May, 2014) [학술회의] 김용성, 김예진, 최혜지, Anti-Met x VEFR2 bispecific antibody based on heterodimeric Fc possesses potent anti-tumor activity , 2014 한국생물공학회 춘계학술발표대회 (Apr, 2014) [학술회의] 김용성, Design of solid tumor-penetrating antibody , 2013 DASAN Conference Health Science , pp.132 -132 (Nov, 2013) [학술회의] 김용성, 최혜지, 김예진, A heterodimeric Fc-based bispecific antibody simultaneously targeting Met and VEGFR-2 demonstrate potent anti-tumor activity , 2013 DASAN Conference Health Science (Nov, 2013) [학술회의] 김용성, 성은실, 김예진, 신태환, Fusion of a neuropilin-targeting peptide to monoclonal antibody improves antibody tumor penetration and anti-tumor efficacy , 2013 DASAN Conference Health Science (Nov, 2013) [학술회의] 김용성, 백두산, Rabbit Immune Library Construction and Isolating Phospho-specific Antibody Using Yeast Surface Display , 2013 한국미생물학회 국제학술대회 및 정기학술대회 , pp.454 -454 (Jul, 2013) [학술회의] 김용성, 신승민, 최동기, 신태환, Comparison of Cellular Internalization Mechanism and Intracellular Trafficking of Transbody and Tat peptide , 2013 한국미생물학회 국제학술대회 및 정기학술대회 (Jul, 2013) [학술회의] 김용성, 김예진, 최혜지, Newly Designed CH3 Domain Mutant Pairs for High Yield Formation of Heterodimeric Fc of Human Antibody , 2013 한국미생물학회 국제학술대회 및 정기학술대회 (Jul, 2013) [학술회의] 김용성, 양석우, 성은실, 이창한, Affinity Maturation of anti-DR5 KD548 by Yeast Surface Display , 2012 KSBB Spring Meeting (Apr, 2012) [학술회의] 김용성, 신태환, 신승민, 김애영, Sequence-specific, Nucleic-acid Hydrolyzing Antibody Degrades Viral Genome RNA and Inhibits the Replication of Influenza H9N2 Virus without Significant Cytotoxicity to Host Cell , 2012 KSBB Spring Meeting (Apr, 2012) [학술회의] 김용성, 박송이, 최혜지, Affinity and Stability Improvement of Human Antibody against Death Receptor 5 , 2012 KSBB Spring Meeting (Apr, 2012) [학술회의] 김용성, 신태환, 권명희, 최동기, Sequence Specific Engineering of anti-DNA Single Domain Antibody for Classical Swine Fever Virus , 2012 KSBB Spring Meeting (Apr, 2012) [학술회의] 김용성, 박경진, 성은실, The Proteasome Inhibitor MG132 Potentiates Death Receptor 4/5 Agonist-Induced Apoptotic Cell Death by Stabilizing tBid and Bik in Human Head and Neck Squamous Cell Carcinoma Cells , 2012 KSBB Spring Meeting (Apr, 2012) [학술회의] 김용성, Interfering Transbody : The new platform technology for cancer and viral therapy , 2011년도 한국생물공학회 추계학술발표대회 및 국제심포지움 (Oct, 2011) [학술회의] 김용성, 이창한, 박경진, TRAIL receptor 1 and 2 induced activation of the Nox1 NADPH oxidase and its role in the induction of caspase-independent apoptotic cell death , 2011 KSBMB Annual Meeting (May, 2011) [학술회의] 김용성, 박보영, 성은실, 김애영, 최동기, Interfering transbody-mediated Her2/neu silencing induces apoptosis by G1 cell cycle arrest in Her2-overexpressing breast cancer cells , 2011 KSBMB Annual Meeting (May, 2011) [학술회의] 김용성, 박경진, 김애영, 이창한, Generation of bivalent and bispecific Kringle single domains by loop grafting as potent agonists against death receptor 4 and 5 , 2011 KSBMB Annual Meeting (May, 2011) [학술회의] 김용성, 박경진, 김애영, 성은실, 김수현, 김정선, 권명희, 이창한, 최지다, Engineering of a Human Kringle Domain into Agonistic and Antagonistic Binding Proteins Functioning in vitro and in vivo , 2010 한국생물공학회 춘계학술대회 , pp.113 -113 (Apr, 2010) [학술회의] 김용성, 이자영, 김정선, 김애영, 권명희, 이우람, 최동기, Target mRNA Downregulation by Cell-penetrating and Nucleic-acid Hydrolyzing Single Domain Antibodies , 2010 한국생물공학회 춘계학술대회 , pp.117 -117 (Apr, 2010) [학술회의] 김용성, 장지영, 이우람, 권명희, 김애영, Gene silencing by cell-penetrating, sequence selective, nucleic-acid hydrolyzing interfering transbody , The 1st. Korean Oligonucleotide Therapeutics Society International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 광운제, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유희, A novel monoclonal antibody against TRAIL receptor 1 induces apoptotic cell death in various cancer cells. , 2009 KSBB Fall Meeting and International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 이창한, 성은실, 권명희, 박경진, A novel Anti-human DR4/5 Kringle domain, KD548-Fc, with tumoricidal activity induces caspase-independent cell death. , 2009 KSBB Fall Meeting and International Symposium. , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 권명희, 김정선, 김동식, Sequence specific engineering of anti-DNA single domain antibody for classical swine fever virus. , 2009 KSBB Fall Meeting and International Symposium. , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 이창한, 김창구, Affinity maturation of novel target-specific binding proteins based on the kringle domain. , 2009 KSBB Fall Meeting and International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 박혜란, 이승현, 박동원, 김진규, 성은실, Humanization of an Agonistic Anti-Death Receptor 4 Single Chain Variable Fragment Antibody and Avidity-Mediated Enhancement of the Cell Death-Inducing Activity , 2009 KSBB Fall Meeting and International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 김수현, 최지다, 박경진, 성은실, 이창한, 권명희, 김정선, Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo. , 2009 KSBB Fall Meeting and International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 이자영, 이우람, 장지영, 권명희, 김정선, Engineering of a Cell-penetrating and Nucleic-acid Hydrolyzing Single Domain Antibody for Sequence-selective mRNA Degradation , 2009 KSBB Fall Meeting and International Symposium , Vol.1 , No.1 , pp.1 -1 (Nov, 2009) [학술회의] 김용성, 장지영, 권명희, 이우람, 김애영, Degradation of target mRNA by cell-penetrating, sequence-selective, nucleic-acid hydrolyzing single domain antibodies. , The 50th Annual meeting and international symposium of Korean Society of Life Science , Vol.1 , No.1 , pp.1 -1 (Oct, 2009) [학술회의] 김용성, 정준호, 곽채원, 박경진, 이승현, 이창한, 권명희, 장지영, Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death , The 17th Federation Meeting of Korean Basic Medical Scientists , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 광운제, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유희, A novel agonistic antibody to human Death Receptor 4 Induces apoptosis cell death in various tumor cells without cytotoxicity in Hepatocyte. , The 17th Federation Meeting of Korean Basic Medical Scientists , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, Development of interfering antibody, iAb: Is it possible to engineer intercellular antibody as an alternative to siRNA ? , 2009 Proceedings of the convention of the Korean Society of Applied Pharmacology : The strategy for , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 이창한, 성은실, 권명희, 박경진, Development of a novel protein scaffold based on Kringle domain fold , 2009 KSBB Spring Meeting and Inernational Symposium. , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 장기환, 김창구, 김세호, A novel mouse monoclonal antibody against human epidermal growth factor receptor. , 2009 KSBB Spring Meeting and Inernational Symposium , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 광운재, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유희, A novel agonistic antibody to human Death Receptor 4 Induces apoptosis cell death in various tumor cells without cytotoxicity in Hepatocyte , 2009 KSBB Spring Meeting and Inernational Symposium , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 정준호, 이창한, 박경진, 이승현, 권명희, 장지영, Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. , 2009 KSBB Spring Meeting and Inernational Symposium. , Vol.1 , No.1 , pp.1 -1 (Apr, 2009) [학술회의] 김용성, 조미영, 박경진, 이승현, 권명희, 곽채원, Affinity and stability improvement of a human scFv antibody against death receptor 5 , The Tenth Korea-China-Japan Joint symposium on Enzyme engineering , Vol.1 , No.1 , pp.72 -72 (Nov, 2008) [학술회의] 김용성, 김동식, 이석찬, 권명희, 김정선, Humanization of a catalytic antibody by loop grafting , The Tenth Korea-China-Japan Joint symposium on Enzyme engineering , Vol.1 , No.1 , pp.59 -59 (Nov, 2008) [학술회의] 김용성, 박경진, 이창한, 권명희, A novel non-antibody protein scaffold based on kringle domain structure , The Tenth Korea-China-Japan Joint symposium on Enzyme engineering , Vol.1 , No.1 , pp.81 -81 (Nov, 2008) [학술회의] 김용성, 장기환, 김창구, 김세호, Affinity maturation of a fully human anti-EGFR scFv antibody , The Tenth Korea-China-Japan Joint symposium on Enzyme engineering , Vol.1 , No.1 , pp.74 -74 (Nov, 2008) [학술회의] 김용성, 곽원재, 박상구, 이승현, 장윤선, 박경진, 성은실, 권명희, 박유회, A novel monoclonal antibody against TRAIL receptor 1 induces apoptotic cell death in a variety of cancer cells , The Tenth Korea-China-Japan Joint symposium on Enzyme engineering , Vol.1 , No.1 , pp.80 -80 (Nov, 2008) [학술회의] 김용성, 이승현, 조미영, 권명희, Production and characterization of an anti-cancer scFv-Fc antibody , 2008 춘계학술발표대회 및 국제심포지움 , Vol.22 , No.1 , pp.213 -213 (Apr, 2008) [학술회의] 권명희, 장지영, 츄옹, 이승현, 이창한, 김용성, 김태인, Synergistic contribution of apoptotic and autophagic signaling through TRAIL receptor 2 to the cell death of cancer cells , 2008 춘계학술발표대회 , Vol.22 , No.1 , pp.212 -212 (Apr, 2008) [학술회의] 김용성, 김태인, 이창한, 성은실, 이승현, 권명희, 박경진, An autophagic cell death signaling pathway triggered by a human scFv antibody against TRAIL receptor 2 , 춘계학술발표대회 및 국제심포지움 , Vol.22 , No.1 , pp.208 -208 (Apr, 2008) [학술회의] 박기동, 정의정, 정윤기, 손세진, 권명희, 김용성, Cytoplasmic delivery of monoclonal antibody with antiviral activity using PLGA nanoparticle , 생체재료 학회 , Vol.11 , No.2 , pp.106 -106 (Nov, 2007) [학술회의] 권명희, 김태인, 장지영, 이창한, 츄옹, 김용성, 박경진, Characterization of a human single chain variable fragment(HW6) against TRAIL receptor 2 , The 55th Fall conference of The Korean Association of Immunologists , Vol.1 , No.1 , pp.123 -123 (Nov, 2007) [학술회의] 김용성, Antibody engineering and biomarker discovery using high-throughput yeast surface display technology , 2007 한국생물공학회 및 국제 심포지움 , Vol.1 , No.1 , pp.89 -89 (Apr, 2007) [학술회의] 김용성, 김민수, 최혜영, 김진국, 최용수, Optimized serological isolation of lung cancer-associated antigens from a yeast surface displayed cDNA library , 2007 한국생물공학회 춘계학술발표대회 및 국제 심포지움 , Vol.1 , No.1 , pp.211 -211 (Apr, 2007) [학술회의] 김용성, Antibody development for the engineering of cellular signaling network , 2006 Annual Meeting and International Symposium of KMB (The Korean Society for Microbiology and Bi , Vol.1 , No.1 , pp.240 -240 (Jun, 2006) [학술회의] 김용성, 이해원, 이승현, 권명희, 박경진, Construction and characterization of a pseudo-immune human antibody library using yeast surface display. , 2006 Annual Meeting and International Symposium of KMB (The Korean Society for Microbiology and Biot , Vol.1 , No.1 , pp.366 -366 (Jun, 2006) [학술회의] 김용성, 이해원, 박경진, 이승현, 권명희, 김태인, A novel anti-DR5 human scFv antibodies induce cell death in multiple tumors in monomeric form , 2006 Annual Meeting and International Symposium of KMB (The Korean Society for Microbiology and Biot , Vol.1 , No.1 , pp.404 -404 (Jun, 2006) [학술회의] 김용성, 이현욱, 이우람, 권명희, 김태인, Generation of Cys230 TRAIL mutant with comparable the trimeric stability and apoptotic efficacy to the wild type , 2006 Annual Meeting and International Symposium of KMB (The Korean Society for Microbiology and Biot , Vol.1 , No.1 , pp.405 -405 (Jun, 2006) [학술회의] 김용성, 최혜영, 김민수, 김진국, Discovery of lung cancer specific biomarker using SEREX and Yeast Surface Display. , 2006 Annual Meeting and International Symposium of KMB (The Korean Society for Microbiology and Biot , Vol.1 , No.1 , pp.407 -407 (Jun, 2006) [학술회의] 김용성, 이현욱, 김태인, 이우람, 권명희, 김정선, TRAIL engineering for the development of potent proapoptotic anti-cancer therapeutics , 2006 Spring KSBB (the Korean Society for Biotechnology and Bioengineering) Annual meeting and Intern , Vol.18 , No.1 , pp.120 -120 (May, 2006) [학술회의] 김용성, 김정선, 이해원, 박경진, 이승현, 권명희, 김영림, Development of potent cancer-cell specific proapoptotic human scFv antibodies against human death receptor 5 from a pseudo-immune library , 2006 Spring KSBB (the Korean Society for Biotechnology and Bioengineering) Annual meeting and Intern , Vol.18 , No.1 , pp.117 -117 (May, 2006) [학술회의] 유연우, 서진호, 최기섭, 김용성, Enhanced coenzyme Q10 productivity by exppolysaccharide deficient Agrobacterium tumefaciens ATCC4452 , 2005년도 국제심포지움 및 추계학술발표대회 , Vol.17 , No.1 , pp.324 -325 (Oct, 2005) [학술회의] 유연우, 강현우, 윤기선, 김용성, Effects of S-adenosylmethionine on secondary metabolite and morphology in Streptomyces avermitilis NRRL8165 and Streptomyces peucetius KCTC9039 , 2005년도 국제심포지움 및 추계학술발표대회 , Vol.17 , No.1 , pp.373 -373 (Oct, 2005) [학술회의] 김용성, 이해원, 이현욱, 이승현, Isolation of human scFv library against human DR5 and DcR1 from non-immune library , 대한 생화학 분자생물학회 , Vol.1 , No.1 , pp.122 -122 (Oct, 2005) [학술회의] 김용성, 이현욱, 이우람, 권명희, TRAIL engineering for the development of Cancer-cell selective proapoptotic inducer , 대한 생화학 분자생물학회 , Vol.1 , No.1 , pp.122 -122 (Oct, 2005) [학술회의] 김용성, 이해원, 이승현, 권명희, 장영주, Isolation of human scFv antibodies against human death receptor 5 and decoy receptor 1 from a pseudo-immune library , 대한 생화학 분자생물학회 , Vol.1 , No.1 , pp.121 -121 (Oct, 2005) [학술회의] 권명희, 신호준, 박선, 김경민, 김용성, Analysis of spacer region left from Cre-mediated recombination between heterologous mutant lox sites , 62nd Annual KSBMB meeting , Vol.2005 , No.1 , pp.146 -146 (May, 2005) [학술회의] 권명희, 김용성, 이승현, 신호준, 최미영, 김영림, 김경민, 박선, Characterization of the scFv of a catalytic anti-DNA antibody 3D8 , 제 50차 춘계학술대회 , Vol.2005 , No.1 , pp.80 -80 (Apr, 2005) [학술회의] 김용성, 유연우, 이해원, 권명희, Development of human Fab antibodies against human death receptors and death decoy receptors from a phage display library , 한국생물공학회 춘계학술대회 , Vol.16 , No.1 , pp.393 -393 (Apr, 2005) [학술회의] 김용성, 이해원, 권명희, 유연우, 이승현, 이현욱, Homomeric and heteromeric interactions of the Extracellular domains of death receptors and death decoy receptors , 한국생물공학회 춘계학술대회 , Vol.16 , No.1 , pp.1205 -1212 (Apr, 2005) [학술회의] 유연우, 김승범, 윤상영, 김용성, Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus , 2005년도 한국생물공학회 춘계학술발표회 , Vol.16 , No.1 , pp.316 -316 (Apr, 2005) [학술회의] 유연우, 서진호, 강희윤, 김용성, Production of xylitol by Candida tropicalis HY200 using repeated-batch fermentation , 2005년도 한국생물공학회 춘계학술발표회 , Vol.16 , No.1 , pp.81 -81 (Apr, 2005) [학술회의] 유연우, 신상흠, 강희윤, 고권혜, 김용성, 강현욱, Production of avermectin from Streptomyces avermitilis NRRL8165 by optimization of medium composition , 2005년도 한국생물공학회 춘계학술발표회 , Vol.16 , No.1 , pp.152 -156 (Apr, 2005) [학술회의] 김용성, 권명희, Protein and antibody engineering by yeast surface display , 2004 KRIBB conference , Vol.1 , No.1 , pp.4 -4 (Dec, 2004) [학술회의] 김용성, Rashna Bhandari, K.Dane Wittrup, Jennifer R.Cochran, John Kuriyan, Directed Evolution of Epidermal Growth Factor Receptor Extracellular domain for the expression in Yeast , 한국생물공학회 2004 춘계학술발표대회 , pp.60 -60 (Apr, 2004) 저서 및 번역 [저서] 김용성, 성은실, TRAIL receptor 1/2 (Death receptor 4/5, DR4/5) in Encyclopedia of signaling molecules , pp.1921-1928 (Nov, 2012)
특허 및 기타	[특허] 김용성, 이세영, CMV pp65 펩타이드/HLA-A02 복합체에 특이적인 TCR-유사 항체 및 이의 용도 (출원) (PCT/KR2020/017067) (Nov, 2020) [특허] 김용성, 김예진, EGFR 표적 제제에 대한 저항성을 억제하기 위한 조성물 (출원) (10-2020-0159921) (Nov, 2020) [특허] 김용성, 이세영, CMV pp65 펩타이드/HLA-A02 복합체에 특이적인 TCR-유사 항체 및 이의 용도 (출원) (10-2020-0138273) (Oct, 2020) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (등록) (10,800,825) (R0420US) (Oct, 2020) [특허] 김용성, 이동현, 정근옥, 박해심, 김정은, 인간 IL-5Rα에 결합하는 항체 및 이의 용도 (출원) (10-2020-0117668) (Sep, 2020) [특허] 김용성, 이동현, 정근옥, 박해심, 김정은, 인터루킨-4 수용체 알파 서브유닛과 인터루킨-5 수용체 알파 서브유닛에 동시에 결합하는 이중특이항체 및 이의 용도 (출원) (10-2020-0117667) (Sep, 2020) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (출원) (17/015,875) (R0420US) (Sep, 2020) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (2892623) (R0420CA) (Aug, 2020) [특허] 김용성, 김예진, 김정아, 정근옥, 뉴로필린 1 (Neuropilin 1, NRP1)에 특이적으로 결합하는 펩타이드를 포함하는 조절 T 세포의 활성을 억제하기 위한 조성물 (출원) (10-2020-0099962) (Aug, 2020) [특허] 김용성, 췌장암 예방 또는 치료용 조성물 (출원) (10-2020-0079372) (Jun, 2020) [특허] 김용성, 이세영, CMV pp65 펩타이드/HLA-A*02 복합체에 특이적인 TCR-유사 항체 및 이의 용도 (출원) (10-2020-0014469) (Feb, 2020) [특허] 김용성, 손민정, 이세영, 김정아, 정근옥, 항원 유래 T 세포 항원 에피토프 또는 이를 포함하는 펩타이드를 세포 표면에 제시하기 위한 융합항체, 및 이를 포함하는 조성물 (출원) (10-2020-0014468) (Feb, 2020) [특허] 김용성, 김정호, 백두산, 뉴로필린1에 특이적으로 결합하는 Non-CendR 펩타이드, 상기 펩타이드가 융합된 융합 단백질 및 이의 용도 (등록) (10-2054389) (Dec, 2019) [특허] 김용성, 최동기, 최혜지, 김예진, 정근옥, 하지희, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 사이토카인 (heterodimeric Fc-fused cytokine) 및 이를 포함하는 약제학적 조성물 (출원) (10-2019-0152270) (Nov, 2019) [특허] 김용성, 최동기, 최혜지, 김예진, 정근옥, 하지희, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 사이토카인 (heterodimeric Fc-fused cytokine) 및 이를 포함하는 약제학적 조성물 (등록) (10-2050463) (Nov, 2019) [특허] 김용성, 김예진, EGFR 표적 제제에 대한 저항성을 억제하기 위한 조성물 (등록) (10-2048474) (Nov, 2019) [특허] 김용성, 김예진, EGFR 표적 제제에 대한 저항성을 억제하기 위한 조성물 (출원) (10-2019-0146629) (Nov, 2019) [특허] 김용성, 정근옥, 김정은, 박해심, 인간 IL-4 수용체 알파에 대한 고친화도 인간 항체 및 이의 용도 (출원) (10-2019-0141549) (Nov, 2019) [특허] 김용성, 정근옥, 김정은, 박해심, 인간 IL-4 수용체 알파에 대한 고친화도 인간 항체 및 이의 용도 (출원) (PCT/KR2019/015083) (Nov, 2019) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 그 용도 (등록) (2013352812) (R0420AU) (Oct, 2019) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (239041) (R0420IL) (Oct, 2019) [특허] 김용성, 김정호, 백두산, 뉴로필린1에 특이적으로 결합하는 Non-CendR 펩타이드, 상기 펩타이드가 융합된 융합 단백질 및 이의 용도 (출원) (10-2019-0110743) (Sep, 2019) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (032681) (R0420EA) (Jul, 2019) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (ZL201380071306.X) (R0420CN) (Apr, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (201780062851.0) (R0420CN) (Apr, 2019) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (출원) (201780061293.6) (R0420CN) (Apr, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (2019/00772) (R0420ZA) (Mar, 2019) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (출원) (17847030.8) (R0420EP) (Mar, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (201947008042) (R0420IN) (Mar, 2019) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (출원) (2019-511858) (R0420JP) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (17839824.4) (R0420EP) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (2017310163) (R0420AU) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (3,033,475) (R0420CA) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (MX/A/2019/001651) (R0420MX) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (11201901071T) (R0420SG) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불면부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (16/233,839) (R0420US) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (2019-506697) (R0420JP) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (264692) (R0420IL) (Feb, 2019) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (BR 11 2019 002394 1) (R0420BR) (Feb, 2019) [특허] 김용성, 이경미, 임선아, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (등록) (10-1928981) (Dec, 2018) [특허] 김용성, 김정은, 정근옥, 박해심, 인간 IL-4 수용체 알파에 대한 고친화도 인간 항체 및 이의 용도 (출원) (10-2018-0137199) (Nov, 2018) [특허] 김용성, 김예진, 김정아, 정근옥, 뉴로필린 1 (Neuropilin 1, NRP1)에 특이적으로 결합하는 펩타이드를 포함하는 조절 T 세포의 활성을 억제하기 위한 조성물 (출원) (10-2018-0107208) (Sep, 2018) [특허] 김용성, 김예진, 김정아, 정근옥, 뉴로필린 1 (Neuropilin 1, NRP1)에 특이적으로 결합하는 펩타이드를 포함하는 조절 T 세포의 활성을 억제하기 위한 조성물 (출원) (PCT/KR2018/010487) (Sep, 2018) [특허] 김용성, 김예진, 성은실, 신태환, 뉴로필린에 특이적인 종양 침투성 펩타이드 및 이 펩타이드가 융합된 융합 단백질 (등록) (6391676) (R0420JP) (Aug, 2018) [특허] 김용성, 김예진, EGFR 표적 제제에 대한 저항성을 억제하기 위한 조성물 (출원) (16/081,342) (R0420US) (Aug, 2018) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (6385357) (R0420JP) (Aug, 2018) [특허] 김용성, 하지희, 최혜지, 효모접합을 이용한 항체 CH3 도메인 이종이중체 돌연변이쌍 제조방법 및 이에 의하여 제조된 CH3 돌연변이체 쌍 (출원) (15/778,966) (R0420US) (May, 2018) [특허] 김용성, 김예진, 성은실, 신태환, 뉴로필린에 특이적인 종양 침투성 펩타이드 및 이 펩타이드가 융합된 융합 단백질 (등록) (9,975,933) (R0420US) (May, 2018) [특허] 김용성, 하지희, 최혜지, 효모접합을 이용한 항체 CH3 도메인 이종이중체 돌연변이쌍 제조방법 및 이에 의하여 제조된 CH3 돌연변이체 쌍 (출원) (16855701.5) (R0420EP) (May, 2018) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (9,951,145) (R0420US) (Apr, 2018) [특허] 김용성, 하지희, 최혜지, 효모접합을 이용한 항체 CH3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 CH3 돌연변이체 쌍 (등록) (10-1851380) (Apr, 2018) [특허] 김용성, 강여울, 홍순선, 췌장암의 예방 또는 치료용 조성물 (출원) (10-2018-0040506) (Apr, 2018) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍,항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (출원) (15/944,505) (R0420US) (Apr, 2018) [특허] 김용성, 홍순선, 강여울, RAS-GTP 타겟 항체 (RT11-i) 및 젬시타빈을 유효성분으로 함유하는 췌장암의 예방 또는 치료용 조성물 (출원) (10-2018-0001246) (Jan, 2018) [특허] 김용성, 김예진, 뉴로필린1 특이적 결합 펩타이드 및 이 펩타이드가 융합된 융합 단백질, 및 이의 용도 (출원) (16769094.0) (R0420EP) (Oct, 2017) [특허] 김용성, 김예진, 뉴로필린1 특이적 결합 펩타이드 및 이 펩타이드가 융합된 융합 단백질, 및 이의 용도 (출원) (2017-549504) (R0420JP) (Sep, 2017) [특허] 김용성, 정근옥, 김정아, 김예진, 뉴로필린 1 (Neuropilin 1, NRP1)에 특이적으로 결합하는 펩타이드를 포함하는 조절 T 세포의 활성을 억제하기 위한 조성물 (출원) (10-2017-0115262) (Sep, 2017) [특허] 김용성, 김예진, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물 (출원) (PCT/KR2017/009570) (Aug, 2017) [특허] 김용성, 하지희, 정근옥, 항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물 (출원) (PCT/KR2017/008676) (Aug, 2017) [특허] 김용성, 정의정, 이우람, 권명희, 동물 세포 감염 바이러스에 대한 항바이러스제 (등록) (9,534,040) (R0420US) (Jan, 2017) [특허] 김용성, 하지희, 최혜지, 효모접합을 이용한 항체 CH3 도메인 이종이중체 돌연변이쌍 제조방법 및 이에 의하여 제조된 CH3 돌연변이체 쌍 (출원) (PCT/KR2016/011396) (Oct, 2016) [특허] 김용성, 정근옥, 하지희, 항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 사이토카인 (heterodimeric Fc-fused cytokine) 및 이를 포함하는 약제학적 조성물 (출원) (10-2016-0101823) (Aug, 2016) [특허] 김용성, 김예진, 뉴로필린1 특이적 결합 펩타이드 및 이 펩타이드가 융합된 융합 단백질, 및 이의 용도 (출원) (PCT/KR2016/002942) (Mar, 2016) [특허] 김용성, 김예진, 성은실, 신태환, 뉴로필린에 특이적인 종양 침투성 펩타이드 및 이 펩타이드가 융합된 융합 단백질 (출원) (14800779.2) (R0420EP) (Dec, 2015) [특허] 김용성, 뉴로필린1 특이적 결합 펩타이드 및 이 펩타이드가 융합된 융합 단백질, 및 이의 용도 (등록) (10-1551306) (Sep, 2015) [특허] 김용성, 김예진, 성은실, 신태환, 뉴로필린에 특이적인 종양 침투성 펩타이드 및 이 펩타이드가 융합된 융합 단백질 (등록) (10-1551299) (Sep, 2015) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (출원) (13859121.9) (R0420EP) (Jun, 2015) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 그 용도 (출원) (5014/DELNP/2015) (R0420IN) (Jun, 2015) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 그 용도 (출원) (BR 1120150123104) (R0420BR) (May, 2015) [특허] 김용성, 성은실, 최혜지, 항체 중쇄불변부위의 이종이중체 고효율 형성을 유도하는 CH3 도메인 변이체 쌍, 이의 제조방법, 및 용도 (등록) (10-1522954) (May, 2015) [특허] 김용성, 이창한, 권명희, 크링글 도메인의 구조에 기반한 단백질 골격 라이브러리 및 그 용도 (등록) (5616890) (R0420JP) (Sep, 2014) [특허] 김용성, 김예진, 성은실, 신태환, 뉴로필린에 특이적인 종양 침투성 펩타이드 및 이 펩타이드가 융합된 융합 단백질 (출원) ( PCT/KR2014/004571) (May, 2014) [특허] 권명희, 김용성, 장지영, 암세포에 세포사멸을 유도하는 항-핵산 항체 및 이를 이용한 암 예방 또는 치료용 조성물 (등록) (EP 2279002) (R0420EP) (Aug, 2013) [특허] 김용성, 이창한, 권명희, 크링글 도메인의 구조에 기반한 단백질 골격 라이브러리 및 그 용도 (등록) (US 8,492,343) (R0420US) (Jul, 2013) [특허] 권명희, 김용성, 김정선, 김태현, 정의정, 심혜경, 이건섭, 이석찬, 이우람, 정유철, 김기윤, 박을용, 동물 세포 감염 바이러스에 대한 항바이러스제 ANTIVIRAL AGENT AGAINST ANIMAL VIRUSES (등록) (ZL 200780042871.8) (R0420CN) (Jul, 2013) [특허] 김용성, 정의정, 이우람, 권명희, 동물 세포 감염 바이러스에 대한 항바이러스제 (등록) (EP 2068906) (R0420EP) (Aug, 2012) [특허] 김용성, 이창한, 권명희, 크링글 도메인의 구조에 기반한 단백질 골격 라이브러리 및 그 용도 (등록) (10-1127476) (Mar, 2012) [특허] 권명희, 이해원, 이승현, 김용성, 박경진, ANTIBODY SPECIFICALLY BINDING TO DR5 AND COSPOSITION FOR PREVENTING OR TREATING CANCERS COMPRISING THE SAME(세포사멸 수용체5(DR7)에 특이적으로 결합하는 항체 및 이를 포함하는 암 예방 또는 치료용 조성물) (등록) (US 8,097,704) (R0420US) (Jan, 2012) [특허] 김용성, 권명희, 동물 세포 감염 바이러스에 대한 항바이러스제 (출원) (US 12/441,965) (R0420US) (Mar, 2009) [특허] 권명희, 김영림, 김용성, 김정선, 김태현, 박을용, 손종남, 송재영, 심혜경, 이건섭, 이석찬, 이승현, 이우람, 정유철, 정의정, 최은진, 김기윤, 동물 세포 감염 바이러스에 대한 항바이러스제 (등록) (10-0890463) (Mar, 2009)

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