교수진

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교수

교수정보의 상세 화면
유태현
이름
유태현
학력
박사
전공
응용화학생명공학전공(과)
정보
연구실 :
팔달관 806호

연구실번호 :
3543

이메일 :
taehyeonyoo@ajou.ac.kr

연구관심분야 :
단백질공학

홈페이지 :
http://www.spelajou.kr
학력
졸업연도/학교/학위
2008.06 California Inst Tech 박사
졸업연도/학교/학위
1998.02 서울대학교 석사
졸업연도/학교/학위
1996.02 서울대학교 학사
경력 2008. 04 - 2011. 08 University of Texas at Austin, 박사후 연구원
1997. 12 - 2003. 05 녹십자, 연구원
논문 및 연구활동
연구활동(주요논문)
  • [논문] 유태현, 민문원, 강택진, Sushma Chauhan, 박장서, 박현지, 김채은, Identification of peptide inhibitors of matrix metalloproteinase 1 using an in-house assay system for the enzyme , ENZYME AND MICROBIAL TECHNOLOGY , Vol.127 , pp.65 -69 (Aug, 2019)
  • [논문] 최상돈, SHAH MASAUD, 서지영, 권혁권, GUI XIANGAI, 김문석, 조은영, 이병성, 김동진, 이상호, 유태현, ACHEK ASMA, 신현준, Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model , JOURNAL OF MEDICINAL CHEMISTRY , Vol.62 , No.14 , pp.6495 -6511 (Jul, 2019)
  • [논문] 유태현, 이유미, 정상택, 정보석, 조미경, 이병성, 박지수, Construction of an immunotoxin via site-specific conjugation of anti-Her2 igG and engineered pseudomonas exotoxin A , JOURNAL OF BIOLOGICAL ENGINEERING , Vol.13 , No.1 , pp.56 -56 (Jun, 2019)
  • [논문] 유태현, 이경호, 김동명, 장연재, Interfacing a personal glucose meter with cell-free protein synthesis for rapid analysis of amino acids , ANALYTICAL CHEMISTRY , Vol.91 , pp.2531 -2535 (Feb, 2019)
  • [논문] 김문석, 유태현, 박상혁, 박준영, 김맑음, 박승훈, Biomimetic Scaffolds for Bone Tissue Engineering , ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY , pp.109 -121 (Nov, 2018)
국제학술논문지
  • [논문] 유태현, 민문원, 강택진, Sushma Chauhan, 박장서, 박현지, 김채은, Identification of peptide inhibitors of matrix metalloproteinase 1 using an in-house assay system for the enzyme , ENZYME AND MICROBIAL TECHNOLOGY , Vol.127 , pp.65 -69 (Aug, 2019)
  • [논문] 최상돈, SHAH MASAUD, 서지영, 권혁권, GUI XIANGAI, 김문석, 조은영, 이병성, 김동진, 이상호, 유태현, ACHEK ASMA, 신현준, Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model , JOURNAL OF MEDICINAL CHEMISTRY , Vol.62 , No.14 , pp.6495 -6511 (Jul, 2019)
  • [논문] 유태현, 이유미, 정상택, 정보석, 조미경, 이병성, 박지수, Construction of an immunotoxin via site-specific conjugation of anti-Her2 igG and engineered pseudomonas exotoxin A , JOURNAL OF BIOLOGICAL ENGINEERING , Vol.13 , No.1 , pp.56 -56 (Jun, 2019)
  • [논문] 유태현, 이경호, 김동명, 장연재, Interfacing a personal glucose meter with cell-free protein synthesis for rapid analysis of amino acids , ANALYTICAL CHEMISTRY , Vol.91 , pp.2531 -2535 (Feb, 2019)
  • [논문] 김문석, 유태현, 박상혁, 박준영, 김맑음, 박승훈, Biomimetic Scaffolds for Bone Tissue Engineering , ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY , pp.109 -121 (Nov, 2018)
  • [논문] 유태현, 이유미, 고병준, 박지수, Peptide-Directed Photo-Cross-Linking for Site-Specific Conjugation of IgG , BIOCONJUGATE CHEMISTRY , Vol.29 , No.10 , pp.3240 -3244 (Oct, 2018)
  • [논문] 유태현, 박현지, Nucleic Acid Detection by a Target-Assisted Proximity Proteolysis Reaction , ACS Sensors , Vol.3 , No.10 , pp.2066 -2070 (Oct, 2018)
  • [논문] 유태현, 최운종, 석주연, 김경진, 임현규, 정규열, 박성훈, 최상진, 양진아, Directed evolution of the 3-hydroxypropionic acid production pathway by engineering aldehyde dehydrogenase using a synthetic selection device , METABOLIC ENGINEERING , Vol.47 , pp.113 -120 (May, 2018)
  • [논문] 유태현, 최운종, Nguyen Hoai Nam, 최상진, 박성훈, 이선구, 김경진, 최상돈, 심증엽, 정규열, 박예섭, NASIR ABDUL, Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD+, for enhancing the production of 3-hydroxypropionic acid , SCIENTIFIC REPORTS , Vol.7 , No.1 , pp.17155(1) -17155(12) (Dec, 2017)
  • [논문] 유태현, 김수연, 고병준, 이병성, An efficient system for incorporation of unnatural amino acids in response to the four-base codon AGGA in Escherichia coli , BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS , Vol.186 , No.11 , pp.3016 -3023 (Nov, 2017)
  • [논문] 유태현, 이경호, 김동명, 장연재, Complementary cell-free translational assay for quantification of amino acids , ANALYTICAL CHEMISTRY , Vol.89 , No.18 , pp.9638 -9642 (Aug, 2017)
  • [논문] 김문석, 권진선, 이병성, 박지훈, 윤정호, 이분열, 김재호, 민병현, 유태현, 박승훈, 이보근, BMP2-immobilized injectable hydrogel for osteogenic differentiation of human periodontal ligament stem cells , SCIENTIFIC REPORTS , Vol.7 , No.6603 , pp.6603(1) -6603(15) (Jul, 2017)
  • [논문] 최상돈, 신현준, SHAH MASAUD, 유태현, 조혜영, ACHEK ASMA, 권혁권, 이병성, 박설희, ANWAR MUHAMMAD AYAZ, TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation , BIOMATERIALS , Vol.126 , pp.49 -60 (May, 2017)
  • [논문] 이광, 이승아, 최기령, 이다연, 김용만, 서찬, 강석, 진문석, 유태현, 강성호, 신태환, 백만정, Quality and freshness of human bone marrow-derived mesenchymal stem cells decrease over time after trypsinization and storage in phosphate-buffered saline , SCIENTIFIC REPORTS , Vol.7 , No.1 , pp.1106 -1106 (Apr, 2017)
  • [논문] 유태현, 손현철, 박성훈, 정규열, 김경진, Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense , SCIENTIFIC REPORTS , Vol.7 , pp.46005 -46005 (Apr, 2017)
  • [논문] 유연우, 김진영, 홍은수, 유태현, 서민덕, 석승현, Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester , APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , pp.1 -10 (Jan, 2017)
  • [논문] 김환명, 신승건, 조명기, 유태현, 허철호, Real-Time Monitoring of Vesicle pH in an Endocytic Pathway using an EGF-Conjugated Two-Photon Probe , CHEMICAL COMMUNICATIONS , pp.1 -4 (Nov, 2016)
  • [논문] 유태현, 김용성, 박성욱, 김동명, 오찬희, 이경호, 양성윤, 박지호, 민승의, Cell-free production and streamlined assay of cytosol-penetrating antibodies , BIOTECHNOLOGY AND BIOENGINEERING , pp.2107 -2112 (Oct, 2016)
  • [논문] 윤현철, 유태현, 양도경, ZHANG CUNQIANG, 박유민, Development of a Matrix Metalloproteinase-2 (MMP-2) Biosensing System by Integrating an Enzyme-mediated Color Development Reaction into a Common Electronics Components Setup , BIOCHIP JOURNAL , Vol.10 , No.3 , pp.198 -207 (Sep, 2016)
  • [논문] 유태현, 박현지, 양도경, A colorimetric protease activity assay method using engineered procaspase-3 enzymes , ANALYTICAL METHODS , Vol.8 , pp.6270 -6276 (Sep, 2016)
  • [논문] 원종인, 서경호, 이선구, 유태현, 추헌수, Separation ef?ciency of free-solution conjugated electrophoresis with drag-tags incorporating a synthetic amino acid , ELECTROPHORESIS , Vol.37 , pp.818 -825 (Mar, 2016)
  • [논문] 유태현, Yuvaraj Ravikumar, 윤형돈, Chong-Soon Lee, Saravanan Prabhu Nadarajan, Incorporating unnatural amino acids to engineer biocatalysts for industrial bioprocess applications , BIOTECHNOLOGY JOURNAL , Vol.10 , No.12 , pp.1862 -1876 (Dec, 2015)
  • [논문] 김용성, 최동기, 김동명, 신승민, 배점일, 유태현, 김지선, 박성욱, Quantitative assessment of cellular uptake and cytosolic access of antibody in living cells by an enhanced split GFP complementation assay , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.467 , No.4 , pp.771 -777 (Nov, 2015)
  • [논문] 유태현, Yuvaraj Ravikumar, 윤형돈, Chong-soon Lee, Saravanan Prabhu Nadarajan, Unnatural amino acid mutagenesis-based enzyme engineering , TRENDS IN BIOTECHNOLOGY , Vol.33 , No.8 , pp.462 -470 (Aug, 2015)
  • [논문] 유태현, 이분열, 신승건, 전종엽, 장경순, 이병성, 최상돈, Incorporation of Unnatural Amino Acids in Response to the AGG Codon , ACS CHEMICAL BIOLOGY , Vol.10 , No.7 , pp.1648 -1653 (Jul, 2015)
  • [논문] 유태현, Kanagavel Deepankumar, Saravanan Prabhu Nadarajan, 윤형돈, 이선구, 홍은영, 김병기, Sam Mathew, Engineering Transaminase for Stability Enhancement and Site-Specific Immobilization through Multiple Noncanonical Amino Acids Incorporation , CHEMCATCHEM , Vol.7 , No.3 , pp.417 -421 (Feb, 2015)
  • [논문] 유태현, David A. Tirrell, Kai P. Yuet, James A. Van Deventer, Cell Surface Display Yields Evolvable, Clickable Antibody Fragments , CHEMBIOCHEM , Vol.15 , No.12 , pp.1777 -1781 (Aug, 2014)
  • [논문] 유태현, 윤현경, 김하진, Engineering β-lactamase zymogens for use in protease activity assays , CHEMICAL COMMUNICATIONS , Vol.50 , No.70 , pp.10155 -10157 (Jul, 2014)
  • [논문] 이현호, 김민근, 오세욱, 김예진, 윤태식, 이혜진, 오민규, 윤여준, 유태현, 정훈상, Robust ZnO nanoparticle embedded memory device using vancomycin conjugate and its biorecognition for electrical charging node , BIOSENSORS & BIOELECTRONICS , Vol.56 , pp.33 -38 (Jun, 2014)
  • [논문] 유연우, 유태현, 김상철, 홍은수, 김진영, 김승범, 윤상영, 박송이, Improving the enantioselectivity of an esterase toward (S)-ketoprofen ethyl ester through protein engineering , JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC , Vol.100 , pp.25 -31 (Feb, 2014)
  • [논문] 유태현, 윤현경, A novel protease activity assay method based on an engineered autoinhibited protein using an enzyme-linked immunoassay , ANALYST , Vol.138 , No.23 , pp.7164 -7168 (Dec, 2013)
  • [논문] 유태현, George Georgiou, Thomas M. Truskett, Jeetain Mittal, Structural Ensemble of an Intrinsically Disordered Polypeptide , JOURNAL OF PHYSICAL CHEMISTRY B , Vol.117 , No.1 , pp.118 -124 (Jan, 2013)
  • [논문] 유태현, 김재호, 정상택, 윤현경, Recent Development of Highly Sensitive Protease Assay Methods: Signal Amplification through Enzyme Cascades , BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , Vol.17 , No.6 , pp.1113 -1119 (Dec, 2012)
  • [논문] 유태현, Sriram Sokalingam, Sun-Gu Lee, Hyun-Jong Paik, Nediljko Budisa, Nagasundarapandian Soundrarajan, Govindan Raghunathan, Conjugation of Proteins by Installing BIO-Orthogonally Reactive Groups at Their N-Termini , PLoS ONE , Vol.7 , No.10 (Oct, 2012)
  • [논문] 최상돈, 김상건, 유태현, Basith Shaherin, Balachandran Manavalan, Roles of Toll-like Receptors in Cancer: A Double-edged Sword for Defense and Offense , ARCHIVES OF PHARMACAL RESEARCH , Vol.35 , No.8 , pp.1297 -1316 (Sep, 2012)
  • [논문] 유태현, Thomas J. Jampo, David A. Tirrell, Frank Trung, Two-strain, cell-selective protein labeling in mixed bacterial cultures , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , pp.8551 -8556 (May, 2012)
  • [논문] 유태현, Brent L. Iverson, George Georgiou, Mark Pogson, Directed evolution of highly selective proteases using a novel FACS based screen that capitalizes on the p53 regulator MDM2 , CHEMBIOCHEM , Vol.13 , No.5 , pp.649 -653 (Mar, 2012)
  • [논문] 유태현, George Georgiou, Brent L. Iverson, Thomas G. Forsthuber, Jason R. Cantor, Aakanksha Dixit, Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.108 , No.4 , pp.1272 -1277 (Jan, 2011)
  • [논문] 유태현, Ahmed H. Zewail, James A. Van Deventer, David A. Tirrell, Oh-Hoon Kwon, Christina M. Othon, Hydration dynamics at fluorinated protein surfaces , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , Vol.107 , No.40 , pp.17101 -17106 (Oct, 2010)
국제학술발표
  • [학술회의] 유태현, 김수연, 이병성, Incorporation of noncanonical amino acids in response to the rare AGG codon,” tRNA 26th conference, Invited Oral Presentation , 26th tRNA conference (Sep, 2016)
  • [학술회의] 유태현, 윤현경, Amplification of protease activity signals via an engineered autoinhibited protein , The 18th symposium of young asian biochemical engineer's community (Oct, 2012)
  • [학술회의] 유태현, Autoinhibited proteins for engineering proteolytic enzymes and developing protease sensors , The 12th Japan-China-Korea Joint Symposium on Enzyme Engineering (May, 2012)
  • [학술회의] David A. Tirrell, Thomas J. Lampo, 유태현, Frank Truong, Directed Evolution of An E. Coli Methionyl-tRNA Synthetase for Two-Strain, Cell-Selective Proteomic Labeling , 2012 AIChE Annual Meeting (Oct, 2011)
  • [학술회의] 유태현, Deimmunization of a bacterial therapeutic enzyme , 2011년도 한국생물공학회 추계학술대회 및 국제심포지움 (Oct, 2011)
국내학술발표
  • [학술회의] 유태현, Engineering protein sequences and compositions , 2011 한국공업화학회 추계 학술대회 (Nov, 2011)
특허 및 기타
  • [특허] 유태현, 이유미, 박지수, 항체와 생리활성물질의 접합방법 (등록) (10-2037336) (Oct, 2019)
  • [특허] 유태현, 박현지, 근접 단백질가수분해 반응에 기반한 표적 핵산 검출방법 (출원) (PCT/KR2019/012891) (Oct, 2019)
  • [특허] 유태현, 이병성, 이유미, 신규 면역독소 제조방법 (출원) (PCT/KR2019/011411) (Sep, 2019)
  • [특허] 유태현, 이유미, 이병성, 신규 면역독소 제조방법 (출원) (10-2019-0098950) (Aug, 2019)
  • [특허] 유태현, 이유미, 박지수, 항체와 생리활성물질의 접합방법 (출원) (PCT/KR2018/014939) (Nov, 2018)
  • [특허] 유태현, 박현지, 근접 단백질가수분해 반응에 기반한 표적 핵산 검출방법 (출원) (10-2018-0119010) (Oct, 2018)
  • [특허] 유태현, 이병성, 이유미, 신규 면역독소 제조방법 (출원) (10-2018-0107079) (Sep, 2018)
  • [특허] 김문석, 박승훈, 권진선, 유태현, 생체활성인자를 포함하는 폴리에스터 공중합체, 생체이식구조체 및 그 제조방법 (등록) (10-1704542) (Feb, 2017)
  • [특허] 유태현, 김하진, 윤현경, 신규한 자가저해 단백질 융합체 및 이의 용도 (등록) (10-1695684) (Jan, 2017)
  • [특허] 유태현, 박현지, 양도경, 프로테아제 센서 및 이를 이용한 프로테아제의 활성 측정 방법 (등록) (10-1674447) (Nov, 2016)
  • [특허] 유태현, 이병성, 고정 펩타이드 제조 방법 (출원) (10-2015-0181817) (Dec, 2015)
  • [특허] 유태현, 양도경, 프로테아제 활성 측정용 센서 및 이를 이용한 프로테아제의 활성 측정 방법 (출원) (10-2015-0172163) (Dec, 2015)
  • [특허] 유태현, 윤현경, 자가저해 단백질을 이용한 프로테아제 활성 측정용 센서, 및 이를 이용한 프로테아제의 활성 측정 방법 (등록) (10-1533345) (Jun, 2015)
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